Performing rapid autopsy for the interrogation of HIV reservoirs.
Journal
AIDS (London, England)
ISSN: 1473-5571
Titre abrégé: AIDS
Pays: England
ID NLM: 8710219
Informations de publication
Date de publication:
01 06 2020
01 06 2020
Historique:
pubmed:
15
4
2020
medline:
9
3
2021
entrez:
15
4
2020
Statut:
ppublish
Résumé
: Rapid autopsy at the end of life in people with HIV (PWH) permits the preservation of valuable tissue specimens for subsequent study of HIV reservoirs. At our institution, we have developed a cohort of PWH who consent to a rapid autopsy to gather a wide range of fluids and tissues with the goal of advancing HIV cure research. The protocol for successfully performing these autopsies has required careful thought and development over months and years. We have now successfully performed six rapid autopsies and detail here our steps to build the study cohort, train and staff a team of more than a dozen personnel, and process and preserve hundreds of samples from each autopsy.
Identifiants
pubmed: 32287073
doi: 10.1097/QAD.0000000000002546
pmc: PMC7780881
mid: NIHMS1656104
pii: 00002030-202006010-00014
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
1089-1092Subventions
Organisme : NIAID NIH HHS
ID : P01 AI131385
Pays : United States
Organisme : NIAID NIH HHS
ID : P30 AI036214
Pays : United States
Organisme : NICHD NIH HHS
ID : R21 HD094646
Pays : United States
Organisme : NIAID NIH HHS
ID : T32 AI007384
Pays : United States
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