A roadmap to advance delirium research: Recommendations from the NIDUS Scientific Think Tank.
biomarkers
definition
delirium
dementia
diagnosis
measurement
pathophysiology
prevention
public health campaign
treatment
Journal
Alzheimer's & dementia : the journal of the Alzheimer's Association
ISSN: 1552-5279
Titre abrégé: Alzheimers Dement
Pays: United States
ID NLM: 101231978
Informations de publication
Date de publication:
05 2020
05 2020
Historique:
pubmed:
16
4
2020
medline:
16
11
2021
entrez:
16
4
2020
Statut:
ppublish
Résumé
Delirium is an acute disorder of attention and cognition. It occurs across the life span, yet it is particularly common among older adults, and is closely linked with underlying neurocognitive disorders. Evidence is mounting that intervening on delirium may represent an important opportunity for delaying the onset or progression of dementia. To accelerate the current understanding of delirium, the Network for Investigation of Delirium: Unifying Scientists (NIDUS) held a conference "Advancing Delirium Research: A Scientific Think Tank" in June 2019. This White Paper encompasses the major knowledge and research gaps identified at the conference: advancing delirium definition and measurement, understanding delirium pathophysiology, and prevention and treatment of delirium. A roadmap of research priorities is proposed to advance the field in a systematic, interdisciplinary, and coordinated fashion. A call is made for an international consortium and biobank targeted to delirium, as well as a public health campaign to advance the field.
Identifiants
pubmed: 32291901
doi: 10.1002/alz.12076
pmc: PMC7317361
mid: NIHMS1598115
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
726-733Subventions
Organisme : NIA NIH HHS
ID : R24 AG054259
Pays : United States
Informations de copyright
© 2020 The Authors. Alzheimer's & Dementia published by Wiley Periodicals, Inc. on behalf of Alzheimer's Association.
Références
Br J Anaesth. 2019 Jan;122(1):60-68
pubmed: 30579407
J Comp Eff Res. 2016 Mar;5(2):193-205
pubmed: 26930385
JAMA. 2010 Jul 28;304(4):443-51
pubmed: 20664045
Crit Care Med. 2019 Jan;47(1):3-14
pubmed: 30339549
Alzheimers Dement. 2020 May;16(5):726-733
pubmed: 32291901
Alzheimers Dement. 2017 Apr;13(4):e1-e85
pubmed: 28342697
PLoS Med. 2016 Oct 18;13(10):e1002148
pubmed: 27755541
Neurology. 2019 Sep 24;93(13):e1260-e1271
pubmed: 31467255
Curr Opin Crit Care. 2015 Oct;21(5):439-44
pubmed: 26263299
Can J Cardiol. 2013 Jun;29(6):652-8
pubmed: 23702356
J Clin Epidemiol. 2016 Dec;80:16-24
pubmed: 27555082
Am J Geriatr Psychiatry. 2018 Oct;26(10):1015-1033
pubmed: 30076080
J Am Geriatr Soc. 2018 Jan;66(1):22-24
pubmed: 28876455
Trials. 2012 Aug 06;13:132
pubmed: 22867278
Am J Geriatr Psychiatry. 2014 Dec;22(12):1513-21
pubmed: 24745562
Neurobiol Aging. 2012 Mar;33(3):603-616.e3
pubmed: 20471138
Am J Geriatr Psychiatry. 2015 Apr;23(4):403-415
pubmed: 25239680
J Neuroinflammation. 2008 Sep 15;5:38
pubmed: 18793399
BMC Anesthesiol. 2019 Feb 23;19(1):25
pubmed: 30797230
Trials. 2007 Nov 26;8:38
pubmed: 18039364
Mol Psychiatry. 2019 Oct;24(10):1533-1548
pubmed: 29875474
Int J Geriatr Psychiatry. 2018 Nov;33(11):1501-1511
pubmed: 28393426
Alzheimers Dement. 2016 Jul;12(7):766-75
pubmed: 27103261
BMJ. 2010 Mar 19;340:c1066
pubmed: 20304934
Brain Behav Immun. 2013 Feb;28:1-13
pubmed: 22884900
JAMA Intern Med. 2015 Apr;175(4):512-20
pubmed: 25643002
Br J Anaesth. 2019 Mar;122(3):350-360
pubmed: 30770053
Sci Rep. 2016 Jul 20;6:29874
pubmed: 27435513
BMC Med. 2018 Feb 28;16(1):29
pubmed: 29490655
BMC Geriatr. 2018 Sep 17;18(1):217
pubmed: 30223771
BMJ Open. 2018 Apr 20;8(4):e020316
pubmed: 29678977
Alzheimers Dement. 2020 Jan;16(1):71-78
pubmed: 31914219
Lancet. 2014 Mar 8;383(9920):911-22
pubmed: 23992774
N Engl J Med. 2012 Jul 5;367(1):30-9
pubmed: 22762316
Can J Anaesth. 2018 Jul;65(7):813-821
pubmed: 29671186
BMC Geriatr. 2015 Feb 10;15:7
pubmed: 25887557
JAMA. 2015 Apr 28;313(16):1619-20
pubmed: 25799162
Chest. 2015 Jan;147(1):94-101
pubmed: 25166725
Int J Geriatr Psychiatry. 2018 Nov;33(11):1479-1500
pubmed: 28585290