The Requirement of Sox2 for the Spinal Cord Motor Neuron Development of Zebrafish.

Sox2 axons development differentiation motor neuron zebrafish

Journal

Frontiers in molecular neuroscience
ISSN: 1662-5099
Titre abrégé: Front Mol Neurosci
Pays: Switzerland
ID NLM: 101477914

Informations de publication

Date de publication:
2020
Historique:
received: 21 10 2019
accepted: 18 02 2020
entrez: 16 4 2020
pubmed: 16 4 2020
medline: 16 4 2020
Statut: epublish

Résumé

Sex-determining region Y box 2 (Sox2), expressed in neural tissues, plays an important role as a transcription factor not only in the pluripotency and proliferation of neuronal cells but also in the opposite function of cell differentiation. Nevertheless, how Sox2 is linked to motor neuron development remains unknown. Here, we showed that Sox2 was localized in the motor neurons of spinal cord by

Identifiants

pubmed: 32292330
doi: 10.3389/fnmol.2020.00034
pmc: PMC7135881
doi:

Types de publication

Journal Article

Langues

eng

Pagination

34

Informations de copyright

Copyright © 2020 Gong, Hu, Huang, Hu, Wang, Zhao, Qian, Wang, Sheng, Lu, Wei and Liu.

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Auteurs

Jie Gong (J)

School of Life Science, Nantong University, Nantong, China.

Songqun Hu (S)

Department of Otorhinolaryngology Head and Neck Surgery, Affiliated Hospital of Nantong University, Nantong, China.

Zigang Huang (Z)

School of Life Science, Nantong University, Nantong, China.

Yuebo Hu (Y)

Key Laboratory of Neuroregeneration of Jiangsu and MOE, Co-innovation Center of Neuroregeneration, Nantong University, Nantong, China.

Xiaoning Wang (X)

Key Laboratory of Neuroregeneration of Jiangsu and MOE, Co-innovation Center of Neuroregeneration, Nantong University, Nantong, China.

Jinxiang Zhao (J)

Key Laboratory of Neuroregeneration of Jiangsu and MOE, Co-innovation Center of Neuroregeneration, Nantong University, Nantong, China.

Peipei Qian (P)

Key Laboratory of Neuroregeneration of Jiangsu and MOE, Co-innovation Center of Neuroregeneration, Nantong University, Nantong, China.

Cheng Wang (C)

School of Life Science, Nantong University, Nantong, China.

Jiajing Sheng (J)

School of Life Science, Nantong University, Nantong, China.

Xiaofeng Lu (X)

School of Life Science, Nantong University, Nantong, China.

Guanyun Wei (G)

School of Life Science, Nantong University, Nantong, China.

Dong Liu (D)

School of Life Science, Nantong University, Nantong, China.
Key Laboratory of Neuroregeneration of Jiangsu and MOE, Co-innovation Center of Neuroregeneration, Nantong University, Nantong, China.

Classifications MeSH