Relapsed ocular squamous surface neoplasia treated with topical interferon alfa-2b.
Interferon α-2β
conjunctival intraepithelial neoplasia
epidermoid carcinoma
impression cytology
limbal neoplasia
ocular squamous surface neoplasia
Journal
Romanian journal of ophthalmology
ISSN: 2501-2533
Titre abrégé: Rom J Ophthalmol
Pays: Romania
ID NLM: 101677459
Informations de publication
Date de publication:
Historique:
entrez:
16
4
2020
pubmed:
16
4
2020
medline:
6
3
2021
Statut:
ppublish
Résumé
A 54-year-old patient presented with a large, fleshy conjunctival lesion in the right eye that had been previously surgically removed in another centre. Diagnosis of Conjunctival intraepithelial neoplasia (CIN) was confirmed by conjunctival impression cytology. The tumor was treated with topical IFN-α-2β (1,000,000 IU/ (ml) adjuvant to surgery for chemoreduction purposes. One month after treatment, the lesion showed almost complete involution, therefore the treatment was continued up to 6 months, and the lesion showed full regression. The patient is currently under periodical follow-up by conjunctival impression cytology. We consider that topical IFN-α-2β can be used in CIN for chemoreduction and/ or curative purposes. We believe that conjunctival impression cytology is a useful and non-invasive method for diagnosis and follow-up in this condition.
Substances chimiques
Antineoplastic Agents
0
Interferon alpha-2
0
Ophthalmic Solutions
0
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
62-65Informations de copyright
©Romanian Society of Ophthalmology.
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