Phenylalanine and valine differentially stimulate milk protein synthetic and energy-mediated pathway in immortalized bovine mammary epithelial cells.

Immortalized bovine mammary epithelial cells Milk protein synthesis Phenylalanine Proteomics Valine

Journal

Journal of animal science and technology
ISSN: 2055-0391
Titre abrégé: J Anim Sci Technol
Pays: Korea (South)
ID NLM: 101661694

Informations de publication

Date de publication:
Mar 2020
Historique:
received: 10 02 2020
revised: 04 03 2020
accepted: 04 03 2020
entrez: 16 4 2020
pubmed: 16 4 2020
medline: 16 4 2020
Statut: ppublish

Résumé

Studies on promoting milk protein yield by supplementation of amino acids have been globally conducted. Nevertheless, there is a lack of knowledge of what pathways affected by individual amino acid in mammary epithelial cells that produce milk in practice. Phenylalanine (PHE) and valine (VAL) are essential amino acids for dairy cows, however, researches on mammary cell levels are still lacking. Thus, the aim of this study was conducted to evaluate the effects of PHE and VAL on milk protein synthesis-related and energy-mediated cellular signaling

Identifiants

pubmed: 32292933
doi: 10.5187/jast.2020.62.2.263
pii: jast-62-2-263
pmc: PMC7142277
doi:

Types de publication

Journal Article

Langues

eng

Pagination

263-275

Informations de copyright

© Copyright 2020 Korean Society of Animal Science and Technology.

Déclaration de conflit d'intérêts

No potential conflict of interest relevant to this article was reported.

Références

Animals (Basel). 2019 Jul 15;9(7):
pubmed: 31311116
J Anim Sci Biotechnol. 2017 Jan 23;8:10
pubmed: 28127425
Horm Metab Res. 2013 Mar;45(3):183-9
pubmed: 22972179
J Nutr. 2006 Jul;136(7):1792-9
pubmed: 16772439
J Mammary Gland Biol Neoplasia. 2014 Mar;19(1):3-17
pubmed: 24221747
J Dairy Sci. 2016 Apr;99(4):3144-3156
pubmed: 26851853
J Dairy Sci. 2017 Aug;100(8):6676-6688
pubmed: 28571990
Cell Biochem Funct. 2011 Apr;29(3):227-34
pubmed: 21394738
J Dairy Sci. 2015 Nov;98(11):7846-55
pubmed: 26342977
Eur J Biochem. 2002 Nov;269(22):5338-49
pubmed: 12423332
Wiley Interdiscip Rev RNA. 2012 Jul-Aug;3(4):543-55
pubmed: 22555874
J Dairy Sci. 2015 Jul;98(7):4499-508
pubmed: 25912861
J Dairy Sci. 2018 Jun;101(6):5502-5514
pubmed: 29550128
J Dairy Sci. 2017 Jul;100(7):5928-5935
pubmed: 28457551
Brain Pathol. 2016 Jan;26(1):3-17
pubmed: 26269128
J Dairy Sci. 2018 Dec;101(12):11354-11363
pubmed: 30268610
Mol Cell Proteomics. 2005 Sep;4(9):1265-72
pubmed: 15958392
Mol Cells. 2013 Jun;35(6):463-73
pubmed: 23694989
J Anim Sci. 2000 Nov;78(11):2927-32
pubmed: 11063318
J Dairy Sci. 1976 Jul;59(7):1254-70
pubmed: 950397
Bioinform Biol Insights. 2011;5:83-98
pubmed: 21698073
J Dairy Res. 2020 Feb;87(1):70-77
pubmed: 32114997

Auteurs

Jungeun Kim (J)

Department of Animal Science and Technology, Sanghuh College of Life Sciences, Konkuk University, Seoul 05029, Korea.
Team of An Educational Program for Specialists in Global Animal Science, Brain Korea 21 Plus Project, Sanghuh College of Life Sciences, Konkuk University, Seoul 05029, Korea.

Jeong-Eun Lee (JE)

Institute of Integrated Technology, CJ CheilJedang, Suwon 16495, Korea.

Jae-Sung Lee (JS)

Department of Animal Science and Technology, Sanghuh College of Life Sciences, Konkuk University, Seoul 05029, Korea.

Jin-Seung Park (JS)

Institute of Integrated Technology, CJ CheilJedang, Suwon 16495, Korea.

Jun-Ok Moon (JO)

Institute of Integrated Technology, CJ CheilJedang, Suwon 16495, Korea.

Hong-Gu Lee (HG)

Department of Animal Science and Technology, Sanghuh College of Life Sciences, Konkuk University, Seoul 05029, Korea.
Team of An Educational Program for Specialists in Global Animal Science, Brain Korea 21 Plus Project, Sanghuh College of Life Sciences, Konkuk University, Seoul 05029, Korea.

Classifications MeSH