Investigating the effects of fipronil on male fertility: Insight into the mechanism of capacitation.
Capacitation
Fipronil
GABA(A) receptor
Male fertility
Spermatozoa
Journal
Reproductive toxicology (Elmsford, N.Y.)
ISSN: 1873-1708
Titre abrégé: Reprod Toxicol
Pays: United States
ID NLM: 8803591
Informations de publication
Date de publication:
06 2020
06 2020
Historique:
received:
05
03
2020
revised:
31
03
2020
accepted:
04
04
2020
pubmed:
16
4
2020
medline:
24
2
2021
entrez:
16
4
2020
Statut:
ppublish
Résumé
Fipronil (FPN) is a widely used phenylpyrazole pesticide for the control of insects and removal of veterinary pet fleas, ticks, etc. Although FPN presents moderate hazards to human health, people are readily exposed in daily life. FPN acts by impairing the central nervous systems of insects by blocking gamma-aminobutyric acid (GABA) and glutamate-activated chloride channels. A previous study demonstrated that GABA and GABA
Identifiants
pubmed: 32294523
pii: S0890-6238(20)30052-6
doi: 10.1016/j.reprotox.2020.04.002
pii:
doi:
Substances chimiques
Insecticides
0
Pyrazoles
0
Adenosine Triphosphate
8L70Q75FXE
L-Lactate Dehydrogenase
EC 1.1.1.27
fipronil
QGH063955F
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1-7Informations de copyright
Copyright © 2020 Elsevier Inc. All rights reserved.