Galectin-3 Identifies a Subset of Macrophages With a Potential Beneficial Role in Atherosclerosis.


Journal

Arteriosclerosis, thrombosis, and vascular biology
ISSN: 1524-4636
Titre abrégé: Arterioscler Thromb Vasc Biol
Pays: United States
ID NLM: 9505803

Informations de publication

Date de publication:
06 2020
Historique:
pubmed: 17 4 2020
medline: 14 7 2020
entrez: 17 4 2020
Statut: ppublish

Résumé

Galectin-3 (formerly known as Mac-2), encoded by the This study reveals a prominent protective role for galectin-3 in regulating macrophage polarization and invasive capacity and, therefore, delaying plaque progression.

Identifiants

pubmed: 32295421
doi: 10.1161/ATVBAHA.120.314252
pmc: PMC7253188
doi:

Substances chimiques

Galectin 3 0
Transforming Growth Factor beta 0
Matrix Metalloproteinase 12 EC 3.4.24.65

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1491-1509

Subventions

Organisme : British Heart Foundation
ID : FS/18/1/33234
Pays : United Kingdom
Organisme : British Heart Foundation
ID : FS/07/053/24069
Pays : United Kingdom
Organisme : British Heart Foundation
ID : PG/15/30/31390
Pays : United Kingdom
Organisme : British Heart Foundation
ID : PG/18/84/34124
Pays : United Kingdom
Organisme : National Centre for the Replacement, Refinement and Reduction of Animals in Research
ID : NC/N003268/1
Pays : United Kingdom
Organisme : British Heart Foundation
ID : PG/18/66/33838
Pays : United Kingdom

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Auteurs

Karina Di Gregoli (K)

From the Laboratory of Cardiovascular Pathology, Bristol Medical School, Faculty of Health Sciences, University of Bristol, England.

Michelle Somerville (M)

From the Laboratory of Cardiovascular Pathology, Bristol Medical School, Faculty of Health Sciences, University of Bristol, England.

Rosaria Bianco (R)

From the Laboratory of Cardiovascular Pathology, Bristol Medical School, Faculty of Health Sciences, University of Bristol, England.

Anita C Thomas (AC)

From the Laboratory of Cardiovascular Pathology, Bristol Medical School, Faculty of Health Sciences, University of Bristol, England.

Aleksandra Frankow (A)

From the Laboratory of Cardiovascular Pathology, Bristol Medical School, Faculty of Health Sciences, University of Bristol, England.

Andrew C Newby (AC)

From the Laboratory of Cardiovascular Pathology, Bristol Medical School, Faculty of Health Sciences, University of Bristol, England.

Sarah J George (SJ)

From the Laboratory of Cardiovascular Pathology, Bristol Medical School, Faculty of Health Sciences, University of Bristol, England.

Christopher L Jackson (CL)

From the Laboratory of Cardiovascular Pathology, Bristol Medical School, Faculty of Health Sciences, University of Bristol, England.

Jason L Johnson (JL)

From the Laboratory of Cardiovascular Pathology, Bristol Medical School, Faculty of Health Sciences, University of Bristol, England.

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Classifications MeSH