Elevated Lipoprotein A in South Asians and the Associated Risk of Cardiovascular Disease: A Systematic Review.
Journal
Current problems in cardiology
ISSN: 1535-6280
Titre abrégé: Curr Probl Cardiol
Pays: Netherlands
ID NLM: 7701802
Informations de publication
Date de publication:
Mar 2021
Mar 2021
Historique:
received:
01
03
2020
accepted:
11
03
2020
pubmed:
17
4
2020
medline:
16
7
2021
entrez:
17
4
2020
Statut:
ppublish
Résumé
South Asians have a premature risk of cardiovascular disease and increased lipoprotein A which enhances their risk. This systematic review evaluates the role of elevated lipoprotein A in cardiovascular disease risk for South Asians. It discusses the pathophysiology, clinical studies, and treatment of elevated lipoprotein A using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses method. A total of 72 articles was incorporated which consisted of clinical studies, case-control and cohort studies, meta-analysis, reviews, and editorials. Cardiovascular disease and myocardial infarction occurs prematurely in South Asians, which is further enhanced with an elevated lipoprotein A. South Asians with an elevated lipoprotein A have an increased risk of coronary artery disease so they should have early enactment of lifestyle modification and aggressive medical management.
Sections du résumé
BACKGROUND
BACKGROUND
South Asians have a premature risk of cardiovascular disease and increased lipoprotein A which enhances their risk.
METHODS
METHODS
This systematic review evaluates the role of elevated lipoprotein A in cardiovascular disease risk for South Asians. It discusses the pathophysiology, clinical studies, and treatment of elevated lipoprotein A using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses method.
RESULTS
RESULTS
A total of 72 articles was incorporated which consisted of clinical studies, case-control and cohort studies, meta-analysis, reviews, and editorials. Cardiovascular disease and myocardial infarction occurs prematurely in South Asians, which is further enhanced with an elevated lipoprotein A.
CONCLUSIONS
CONCLUSIONS
South Asians with an elevated lipoprotein A have an increased risk of coronary artery disease so they should have early enactment of lifestyle modification and aggressive medical management.
Identifiants
pubmed: 32295712
pii: S0146-2806(20)30058-X
doi: 10.1016/j.cpcardiol.2020.100581
pii:
doi:
Substances chimiques
Lipoprotein(a)
0
Types de publication
Journal Article
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
100581Informations de copyright
Copyright © 2020 Elsevier Inc. All rights reserved.