Early repatriation post-thrombectomy: a model of care which maximises the capacity of a stroke network to treat patients with large vessel ischaemic stroke.


Journal

Journal of neurointerventional surgery
ISSN: 1759-8486
Titre abrégé: J Neurointerv Surg
Pays: England
ID NLM: 101517079

Informations de publication

Date de publication:
Dec 2020
Historique:
received: 05 12 2019
revised: 22 02 2020
accepted: 25 02 2020
pubmed: 17 4 2020
medline: 9 2 2021
entrez: 17 4 2020
Statut: ppublish

Résumé

Healthcare systems are challenged to provide access to thrombectomy in acute stroke patients. Either the "drip and ship" or "mothership" models result in increased numbers of patients in the endovascular stroke centre (ESC). We describe our approach for a "drip, ship, retrieve and leave" model repatriating patients immediately or within 24 hours of thrombectomy. We included consecutive patients who underwent thrombectomy from January 2016 to June 2018. Patients from local region primary stroke centres (PSC) are immediately repatriated and those from remote region PSCs are admitted for 24 hours before repatriation. Key parameters recorded included clinical, radiological and timeline data as well as 90-day modified Rankin Scale (mRS). Patients who stayed beyond the intended time period in the ESC were analysed. From January 2016 to June 2018, 435 patients were transferred, with 352 patients in the local region group and 83 in the remote region group. The median NIHSS was 16 with a median ASPECTS of 9. Good functional outcome was seen in 47% of patients with a mortality rate of 19%. The local region group that were repatriated at the intended time period had a 90-day mRS 0-2 of 47% compared with 20% of those admitted to the ESC (P=0.006). Mortality rates were 20% and 27% respectively (P=0.377). The remote region group, repatriated at 24 hours' post-emergency endovascular thrombectomy had 90-day mRS 0-2 of 65% compared with 41% in the group admitted (P=0.042). Mortality rates were 4% and 22% respectively (P=0.007). This model enables the treatment of large numbers of patients with large vessel occlusion acute ischaemic stroke with thrombectomy within a national stroke service and system of care which would not otherwise be facilitated.

Sections du résumé

BACKGROUND AND PURPOSE OBJECTIVE
Healthcare systems are challenged to provide access to thrombectomy in acute stroke patients. Either the "drip and ship" or "mothership" models result in increased numbers of patients in the endovascular stroke centre (ESC). We describe our approach for a "drip, ship, retrieve and leave" model repatriating patients immediately or within 24 hours of thrombectomy.
METHODS METHODS
We included consecutive patients who underwent thrombectomy from January 2016 to June 2018. Patients from local region primary stroke centres (PSC) are immediately repatriated and those from remote region PSCs are admitted for 24 hours before repatriation. Key parameters recorded included clinical, radiological and timeline data as well as 90-day modified Rankin Scale (mRS). Patients who stayed beyond the intended time period in the ESC were analysed.
RESULTS RESULTS
From January 2016 to June 2018, 435 patients were transferred, with 352 patients in the local region group and 83 in the remote region group. The median NIHSS was 16 with a median ASPECTS of 9. Good functional outcome was seen in 47% of patients with a mortality rate of 19%. The local region group that were repatriated at the intended time period had a 90-day mRS 0-2 of 47% compared with 20% of those admitted to the ESC (P=0.006). Mortality rates were 20% and 27% respectively (P=0.377). The remote region group, repatriated at 24 hours' post-emergency endovascular thrombectomy had 90-day mRS 0-2 of 65% compared with 41% in the group admitted (P=0.042). Mortality rates were 4% and 22% respectively (P=0.007).
CONCLUSION CONCLUSIONS
This model enables the treatment of large numbers of patients with large vessel occlusion acute ischaemic stroke with thrombectomy within a national stroke service and system of care which would not otherwise be facilitated.

Identifiants

pubmed: 32295836
pii: neurintsurg-2019-015667
doi: 10.1136/neurintsurg-2019-015667
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1166-1171

Informations de copyright

© Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Auteurs

Emma Griffin (E)

Interventional Neuroradiology Service, Department of Radiology, Beaumont Hospital, Dublin 9, Ireland emma.griffin.2@ucdconnect.ie.
Royal College of Surgeons, Dublin 2, Ireland.

Sean Murphy (S)

Royal College of Surgeons, Dublin 2, Ireland.
Department of Geriatric and Stroke Medicine, Mater Misericordiae University Hospital, Dublin 7, Ireland.
UCD School of Medicine, Dublin, Ireland.

Mark Sheehan (M)

Interventional Neuroradiology Service, Department of Radiology, Beaumont Hospital, Dublin 9, Ireland.

Sarah Power (S)

Interventional Neuroradiology Service, Department of Radiology, Beaumont Hospital, Dublin 9, Ireland.

Paul Brennan (P)

Interventional Neuroradiology Service, Department of Radiology, Beaumont Hospital, Dublin 9, Ireland.

Alan O'Hare (A)

Interventional Neuroradiology Service, Department of Radiology, Beaumont Hospital, Dublin 9, Ireland.

Seamus Looby (S)

Interventional Neuroradiology Service, Department of Radiology, Beaumont Hospital, Dublin 9, Ireland.

Sebastian McWilliams (S)

Interventional Neuroradiology Service, Department of Radiology, Beaumont Hospital, Dublin 9, Ireland.

Barry Moynihan (B)

Department of Geriatric and Stroke Medicine, Beaumont Hospital, Dublin 9, Ireland.

David Williams (D)

Royal College of Surgeons, Dublin 2, Ireland.
Department of Geriatric and Stroke Medicine, Beaumont Hospital, Dublin 9, Ireland.

Karl Boyle (K)

Department of Geriatric and Stroke Medicine, Beaumont Hospital, Dublin 9, Ireland.

Damien O'Neill (D)

Interventional Neuroradiology Service, Department of Radiology, Beaumont Hospital, Dublin 9, Ireland.

Ronan Collins (R)

Department of Geriatric and Stroke Medicine, Tallaght University Hospital, Dublin 24, Ireland.

Eamon Dolan (E)

Department of Geriatric and Stroke Medicine, Connolly Hospital Blanchardstown, Dublin 15, Ireland.

Tim Cassidy (T)

Department of Geriatric and Stroke Medicine, St Vincent's University Hospital, Dublin 4, Ireland.

Joe Harbison (J)

Department of Geriatric and Stroke Medicine, St. James' Hospital, Dublin 3, Ireland.

Margaret O'Connor (M)

Department of Geriatric and Stroke Medicine, University Hospital Limerick, Limerick, Ireland.

Jack Alderson (J)

Interventional Neuroradiology Service, Department of Radiology, Beaumont Hospital, Dublin 9, Ireland.
Royal College of Surgeons, Dublin 2, Ireland.

John Thornton (J)

Interventional Neuroradiology Service, Department of Radiology, Beaumont Hospital, Dublin 9, Ireland.
Royal College of Surgeons, Dublin 2, Ireland.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH