LDL uptake-dependent phosphatidylethanolamine translocation to the cell surface promotes fusion of osteoclast-like cells.

Animals Atherosclerosis Cholesterol, LDL Lipoproteins, LDL Mice Mice, Inbred C57BL Mice, Knockout Osteoclasts Phosphatidylethanolamines Receptors, LDL / genetics
ATP binding cassette G1 transporter Cell–cell fusion Cholesterol Low-density lipoprotein receptor Osteoclast-like cells Phosphatidylethanolamine

Journal

Journal of cell science
ISSN: 1477-9137
Titre abrégé: J Cell Sci
Pays: England
ID NLM: 0052457

Informations de publication

Date de publication:
27 05 2020
Historique:
received: 14 01 2020
accepted: 25 03 2020
pubmed: 17 4 2020
medline: 22 6 2021
entrez: 17 4 2020
Statut: epublish

Résumé

Osteoporosis is associated with vessel diseases attributed to hyperlipidemia, and bone resorption by multinucleated osteoclasts is related to lipid metabolism. In this study, we generated low-density lipoprotein receptor (

Identifiants

DOI: 10.1242/jcs.243840 PMID: 32295848
pubmed: 32295848
pii: jcs.243840
doi: 10.1242/jcs.243840
pii:
doi:

Substances chimiques

Cholesterol, LDL 0
Lipoproteins, LDL 0
Phosphatidylethanolamines 0
Receptors, LDL 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2020. Published by The Company of Biologists Ltd.

Déclaration de conflit d'intérêts

Competing interestsThe authors declare no competing or financial interests.

Auteurs

Victor J F Kitano (VJF)

Division of Oral Anatomy, Meikai University School of Dentistry, Sakado, Saitama 350-0283, Japan.
Division of Oral and Maxillofacial Surgery, Meikai University School of Dentistry, Sakado, Saitama 350-0283, Japan.
ORCID: 0000-0003-4001-5701

Yoko Ohyama (Y)

Division of Oral Anatomy, Meikai University School of Dentistry, Sakado, Saitama 350-0283, Japan.
Division of Oral and Maxillofacial Surgery, Meikai University School of Dentistry, Sakado, Saitama 350-0283, Japan.

Chiyomi Hayashida (C)

Division of Oral Anatomy, Meikai University School of Dentistry, Sakado, Saitama 350-0283, Japan.

Junta Ito (J)

Josai University, Faculty of Pharmacy and Pharmaceutical Sciences, Department of Clinical Dietetics and Human Nutrition, Sakado, Saitama 350-0295, Japan.

Mari Okayasu (M)

Division of Oral-maxillofacial Surgery, Dentistry and Orthodontics, The University of Tokyo Hospital, Hongo, Tokyo 113-8655, Japan.

Takuya Sato (T)

Division of Oral Anatomy, Meikai University School of Dentistry, Sakado, Saitama 350-0283, Japan.

Toru Ogasawara (T)

Division of Oral-maxillofacial Surgery, Dentistry and Orthodontics, The University of Tokyo Hospital, Hongo, Tokyo 113-8655, Japan.

Maki Tsujita (M)

Department of Biochemistry, Graduate School of Medical Sciences, Nagoya City University, Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, Aichi 467-8601, Japan.
ORCID: 0000-0003-1108-621X

Akemi Kakino (A)

Department of Physiology, Shinshu University School of Medicine, Matsumoto, Nagano 390-8621, Japan.
ORCID: 0000-0002-9612-4256

Jun Shimada (J)

Division of Oral and Maxillofacial Surgery, Meikai University School of Dentistry, Sakado, Saitama 350-0283, Japan.

Tatsuya Sawamura (T)

Department of Physiology, Shinshu University School of Medicine, Matsumoto, Nagano 390-8621, Japan.
ORCID: 0000-0002-5415-2080

Yoshiyuki Hakeda (Y)

Division of Oral Anatomy, Meikai University School of Dentistry, Sakado, Saitama 350-0283, Japan y-hakeda@dent.meikai.ac.jp.
ORCID: 0000-0001-7233-2600

Articles similaires

Evaluating the efficacy of telesurgery with dual console SSI Mantra Surgical Robotic System: experiment on animal model and clinical trials.

Sudhir Prem Srivastava, Vishwajyoti Pascual Srivastava, Avinesh Singh et al.
1.00
Robotic Surgical Procedures Animals Humans Telemedicine Models, Animal

Odour generalisation and detection dog training.

Lyn Caldicott, Thomas W Pike, Helen E Zulch et al.
1.00
Animals Odorants Dogs Generalization, Psychological Smell

FBXO22 inhibits colitis and colorectal carcinogenesis by regulating the degradation of the S2448-phosphorylated form of mTOR.

Minle Li, Xuan Chen, Pengfei Qu et al.
1.00
Animals TOR Serine-Threonine Kinases Colorectal Neoplasms Colitis Mice

Use of organic material provided by an automatic enrichment device by weaner pigs and its influence on tail lesions.

Philipp Heseker, Jeanette Probst, Stefanie Ammer et al.
1.00
Animals Tail Swine Behavior, Animal Animal Husbandry

Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › LDL uptake-dependent phosphatidylethanolamine...
questionsmedicales.fr › Maladies cardiovasculaires › Maladies vasculaires › Artériopathies oblitérantes › Artériosclérose › Athérosclérose › LDL uptake-dependent phosphatidylethanolamine...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Lipoprotéines › Lipoprotéines LDL › Cholestérol LDL › LDL uptake-dependent phosphatidylethanolamine...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Lipoprotéines › Lipoprotéines LDL › LDL uptake-dependent phosphatidylethanolamine...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › LDL uptake-dependent phosphatidylethanolamine...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Lignées consanguines de souris › Souris de lignée C57BL › LDL uptake-dependent phosphatidylethanolamine...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Souris transgéniques › Souris knockout › LDL uptake-dependent phosphatidylethanolamine...
questionsmedicales.fr › Cellules › Cellules myéloïdes › Ostéoclastes › LDL uptake-dependent phosphatidylethanolamine...
questionsmedicales.fr › Lipides › Lipides membranaires › Phospholipides › Glycérophosphate › Acides phosphatidiques › Glycérophospholipides › Phosphatidyléthanolamine › LDL uptake-dependent phosphatidylethanolamine...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs aux lipoprotéines › Récepteurs aux lipoprotéines LDL › LDL uptake-dependent phosphatidylethanolamine...