Left atrial appendage closure in patients with chronic kidney disease: results from the German multicentre LAARGE registry.
Aged
Aged, 80 and over
Atrial Appendage
/ surgery
Atrial Fibrillation
/ complications
Cardiac Surgical Procedures
/ methods
Female
Follow-Up Studies
Germany
Glomerular Filtration Rate
/ physiology
Humans
Male
Prospective Studies
Registries
Renal Insufficiency, Chronic
/ complications
Septal Occluder Device
Treatment Outcome
Atrial fibrillation
Chronic kidney disease
LAARGE
Left atrial appendage
Left atrial appendage closure
Journal
Clinical research in cardiology : official journal of the German Cardiac Society
ISSN: 1861-0692
Titre abrégé: Clin Res Cardiol
Pays: Germany
ID NLM: 101264123
Informations de publication
Date de publication:
Jan 2021
Jan 2021
Historique:
received:
12
01
2020
accepted:
23
03
2020
pubmed:
17
4
2020
medline:
18
8
2021
entrez:
17
4
2020
Statut:
ppublish
Résumé
Chronic kidney disease (CKD) is associated with an increased complication rate after cardiac interventions. Although CKD has a high prevalence among atrial fibrillation patients, the impact of CKD on periprocedural complications and the outcome after an interventional left atrial appendage closure (LAAC) is unclear. The present study, therefore, aimed to investigate whether CKD influences the procedure's effectiveness and safety. LAARGE is a prospective, non-randomised registry. LAAC was conducted with different standard commercial devices, and the follow-up period was one year. CKD was defined by an eGFR < 60 mL/min/1.73 m Two hundred ninety-nine of 623 patients (48.0%) revealed a CKD. The prevalence of cardiovascular comorbidity, CHA Despite an increased cardiovascular risk profile of CKD patients, device implantation was safe, and LAAC was associated with effective stroke prevention across all CKD stages.
Identifiants
pubmed: 32296971
doi: 10.1007/s00392-020-01638-5
pii: 10.1007/s00392-020-01638-5
pmc: PMC7806558
doi:
Types de publication
Journal Article
Multicenter Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
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