Progression to hypertension in youth and young adults with type 1 or type 2 diabetes: The SEARCH for Diabetes in Youth Study.


Journal

Journal of clinical hypertension (Greenwich, Conn.)
ISSN: 1751-7176
Titre abrégé: J Clin Hypertens (Greenwich)
Pays: United States
ID NLM: 100888554

Informations de publication

Date de publication:
05 2020
Historique:
received: 28 10 2019
revised: 10 02 2020
accepted: 29 02 2020
pubmed: 17 4 2020
medline: 20 5 2021
entrez: 17 4 2020
Statut: ppublish

Résumé

Central obesity may contribute to the development of hypertension in youths with diabetes. The SEARCH for Diabetes in Youth Study followed 1518 youths with type 1 diabetes (T1D) and 177 with type 2 diabetes (T2D) diagnosed when <20 years of age for incident hypertension. Incident hypertension was defined as blood pressure ≥95th percentile (or ≥130/80 mm Hg) or reporting antihypertensive therapy among those without hypertension at baseline. Poisson regression models were stratified by diabetes type and included demographic and clinical factors, clinical site, and waist-to-height ratio (WHtR). Youths with T2D were more likely to develop hypertension than those with T1D (35.6% vs 14.8%, P < .0001). For each 0.01 unit of annual increase in WHtR, adjusted relative risk for hypertension was 1.53 (95% CI 1.36-1.73) and 1.20 (95% CI 1.00-1.43) for youths with T1D and T2D, respectively. Effective strategies targeted toward reducing central obesity may reduce hypertension among youths with diabetes.

Identifiants

pubmed: 32297456
doi: 10.1111/jch.13849
pmc: PMC7383720
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

888-896

Subventions

Organisme : NIDDK NIH HHS
ID : P30 DK057516
Pays : United States
Organisme : NCCDPHP CDC HHS
ID : U18 DP006139
Pays : United States
Organisme : NCCDPHP CDC HHS
ID : U01 DP000250
Pays : United States
Organisme : NCCDPHP CDC HHS
ID : U18 DP002714
Pays : United States
Organisme : NCCDPHP CDC HHS
ID : U18 DP002709
Pays : United States
Organisme : NCCDPHP CDC HHS
ID : U18 DP006136
Pays : United States
Organisme : NCCDPHP CDC HHS
ID : U01 DP000246
Pays : United States
Organisme : NCCDPHP CDC HHS
ID : U01 DP000254
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR000062
Pays : United States
Organisme : NCCDPHP CDC HHS
ID : U18 DP002710
Pays : United States
Organisme : NCCDPHP CDC HHS
ID : U18 DP006138
Pays : United States
Organisme : NCCDPHP CDC HHS
ID : U18 DP002708
Pays : United States
Organisme : NCCDPHP CDC HHS
ID : U18 DP006133
Pays : United States
Organisme : NCCDPHP CDC HHS
ID : U18 DP006131
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR000423
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001450
Pays : United States
Organisme : NCCDPHP CDC HHS
ID : U01 DP000247
Pays : United States
Organisme : NIDDK NIH HHS
ID : UC4 DK108173
Pays : United States
Organisme : NCCDPHP CDC HHS
ID : U01 DP000244
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR000154
Pays : United States
Organisme : NCCDPHP CDC HHS
ID : U01 DP000248
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001425
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR002319
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR000077
Pays : United States
Organisme : NCCDPHP CDC HHS
ID : U18 DP006134
Pays : United States

Informations de copyright

© 2020 The Authors. The Journal of Clinical Hypertension published by Wiley Periodicals LLC.

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Auteurs

Corinna Koebnick (C)

Department of Research & Evaluation, Kaiser Permanente Southern California, Pasadena, CA, USA.

Giuseppina Imperatore (G)

Division of Diabetes Translation, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA.

Elizabeth T Jensen (ET)

Department of Epidemiology and Prevention, Wake Forest School of Medicine, Winston-Salem, NC, USA.

Jeanette M Stafford (JM)

Department of Biostatistics and Data Science, Wake Forest School of Medicine, Winston-Salem, NC, USA.

Amy S Shah (AS)

Department of Pediatrics, Cincinnati Children's Hospital and University of Cincinnati, Cincinnati, OH, USA.

Amy K Mottl (AK)

Division of Nephrology and Hypertension, University of North Carolina School of Medicine, Chapel Hill, NC, USA.

Ronny A Bell (RA)

Department of Public Health, East Carolina University, Greenville, NC, USA.

Dana Dabelea (D)

Department of Epidemiology, Colorado School of Public Health, University of Colorado, Aurora, CO, USA.

Angela D Liese (AD)

Department of Epidemiology and Biostatistics, University of South Carolina, Columbia, SC, USA.

Santica M Marcovina (SM)

Northwest Lipid Metabolism and Diabetes Research Laboratories, University of Washington, Seattle, WA, USA.

Ralph B D'Agostino (RB)

Department of Biostatistics and Data Science, Wake Forest School of Medicine, Winston-Salem, NC, USA.

Elaine M Urbina (EM)

The Heart Institute, Cincinnati Children's Hospital Medical Center and University of Cincinnati, Cincinnati, OH, USA.

Jean M Lawrence (JM)

Department of Research & Evaluation, Kaiser Permanente Southern California, Pasadena, CA, USA.

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