Acute myeloid leukemia transformed to a targetable disease.
FLT3
IDH1/2
acute myeloid leukemia
crenolanib
enasidenib
gemtuzumab ozogamicin
gilteritinib
ivosidenib
midostaurin
quizartinib
Journal
Future oncology (London, England)
ISSN: 1744-8301
Titre abrégé: Future Oncol
Pays: England
ID NLM: 101256629
Informations de publication
Date de publication:
May 2020
May 2020
Historique:
pubmed:
17
4
2020
medline:
9
2
2021
entrez:
17
4
2020
Statut:
ppublish
Résumé
Acute myeloid leukemia (AML) is a heterogeneous neoplasm characterized by the monoclonal proliferation of immature progenitors. It is the most common acute leukemia in adults and its incidence increases with age. The standard traditional treatment in fit patients was the '3 + 7' regimen and cytarabine consolidation followed or not with allogeneic stem cell transplantation. Recently, several targeted therapies such as gemtuzumab ozogamicin targeting the CD33
Identifiants
pubmed: 32297538
doi: 10.2217/fon-2019-0670
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM