Erdheim-Chester disease presenting with cough, abdominal pain, and headache.

CT imaging Early diagnosis Rare disease

Journal

Radiology case reports
ISSN: 1930-0433
Titre abrégé: Radiol Case Rep
Pays: Netherlands
ID NLM: 101467888

Informations de publication

Date de publication:
Jun 2020
Historique:
received: 03 12 2019
revised: 05 03 2020
accepted: 06 03 2020
entrez: 18 4 2020
pubmed: 18 4 2020
medline: 18 4 2020
Statut: epublish

Résumé

Erdheim-Chester disease (ECD) is a rare non-Langerhans cell histiocytic disorder. The diagnosis was based on the relationship between radiologic findings, clinical manifestations, and pathologic features of the bone biopsy. We report a case of ECD with unusual presenting symptoms: a 56 year-old man presented with cough, abdominal pain, and recurrent episodes of headache associated without any seizures. Peculiar computer tomography (CT) findings were key for the diagnostic suspicion. Bone biopsy and other radiological investigations confirmed the diagnosis. CT findings can help raise the suspicion of ECD. CT is easy to perform and widely available in comparison with kinetic cardiac magnetic resonance imaging and nuclear imaging. Therefore, CT findings of ECD can reduce the therapeutic delay between diagnosis and therapy prescription.

Identifiants

pubmed: 32300470
doi: 10.1016/j.radcr.2020.03.008
pii: S1930-0433(20)30088-1
pmc: PMC7152688
doi:

Types de publication

Case Reports

Langues

eng

Pagination

745-748

Informations de copyright

© 2020 The Authors. Published by Elsevier Inc. on behalf of University of Washington.

Références

Mayo Clin Proc. 2014 Jul;89(7):985-96
pubmed: 24814521
Mod Pathol. 2018 Apr;31(4):581-597
pubmed: 29192649
Curr Rheumatol Rep. 2014 Apr;16(4):412
pubmed: 24532298
Blood. 2014 Jul 24;124(4):483-92
pubmed: 24850756
Intern Med. 2009;48(1):83-4
pubmed: 19122364
Blood. 2016 May 19;127(20):2375-90
pubmed: 26980727
J Stroke Cerebrovasc Dis. 2017 Aug;26(8):e153-e155
pubmed: 28623120
Orphanet J Rare Dis. 2013 Sep 08;8:137
pubmed: 24011030
Case Rep Oncol. 2017 Jul 11;10(2):613-619
pubmed: 28868020
Radiology. 2010 May;255(2):586-94
pubmed: 20413768
Blood Adv. 2017 Feb 14;1(6):357-366
pubmed: 28553668
Eur J Intern Med. 2015 May;26(4):223-9
pubmed: 25865950
J Nucl Med. 2018 May;59(5):774-779
pubmed: 29097410
Clin Radiol. 2004 Dec;59(12):1136-41
pubmed: 15556598
Neurology. 2009 Dec 15;73(24):2120-2
pubmed: 20018640
Arthritis Rheum. 2009 Oct;60(10):3128-38
pubmed: 19790052
Blood. 2011 Mar 10;117(10):2778-82
pubmed: 21239701

Auteurs

Paola Crivelli (P)

AOU Sassari, Institute of Diagnostic Imaging 2, Italy.

Roberta Eufrasia Ledda (RE)

Section of Radiology, Unit of Surgical Sciences, Department of Medicine and Surgery (DiMeC), University of Parma, Parma, Italy.

Marcello Carboni (M)

AOU Sassari, Institute of Diagnostic Imaging 2, Italy.

Antonella Balestrieri (A)

Department of Radiology, Azienda Ospedaliero Universitaria di Cagliari, Cagliari, Italy.

Maria Alessandra Sotgiu (MA)

Department of Biomedical Sciences, University of Sassari, Sassari, Italy.

Luca Saba (L)

Department of Radiology, Azienda Ospedaliero Universitaria di Cagliari, Cagliari, Italy.

Maurizio Conti (M)

Department of Clinical and Experimental Medicine, Institute of Diagnostic Imaging 2, University of Sassari, Sassari, Italy.

Classifications MeSH