Endoscopic resection of early squamous neoplasia of the oesophagus: long-term follow-up in a UK population from a tertiary hospital.
Journal
European journal of gastroenterology & hepatology
ISSN: 1473-5687
Titre abrégé: Eur J Gastroenterol Hepatol
Pays: England
ID NLM: 9000874
Informations de publication
Date de publication:
07 2020
07 2020
Historique:
pubmed:
18
4
2020
medline:
16
7
2021
entrez:
18
4
2020
Statut:
ppublish
Résumé
To review the efficacy and outcomes of endoscopic resection in the diagnosis and treatment of oesophageal squamous dysplasia and early neoplasia. This was a retrospective study between May 2012-2018. Twenty-one patients were treated with or considered for treatment with endoscopic resection at a tertiary hospital in the UK. The primary outcome was curative resection, defined as histologically proven complete resection of the lesion with deep/vertical margin ≥1 mm from neoplasia. Secondary outcomes were changes in staging from endoscopic resection histology, whether there was a complete reversal of dysplasia at 12-months or the latest endoscopic follow-up and 5-year overall survival rate. Seventeen patients (mean age = 66.5 years) with 20 lesions (35% en-bloc; 65% piecemeal resections) had endoscopic resection performed. Complete resection was achieved in 90% of lesions by endoscopic criteria, but this was confirmed in fewer lesions histologically. Curative resection was achieved histologically in 60% of lesions (11 patients) and noncurative resection in 40% of lesions (6 patients). Changes in staging from endoscopic resection histology were found in 79.2% of lesions (41.7% upstaged; 37.5% downstaged). No patients were found to have recurrence at their 12-month endoscopic follow-up. Eight of the 11 patients (72.7%) with curative resection remained clear of dysplasia/neoplasia throughout their follow-up (mean, 24.3 months; median, 19 months). The five-year overall survival rate was 64%. In UK, endoscopic resection is useful in the management of early squamous neoplasia both for staging and (by piecemeal endoscopic resection in elderly unfit) for medium- to long-term disease clearance.
Identifiants
pubmed: 32302087
doi: 10.1097/MEG.0000000000001692
pii: 00042737-202007000-00003
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
789-796Références
Yip HC, Chiu PW. Endoscopic diagnosis and management of early squamous cell carcinoma of esophagus. J Thorac Dis. 2017; 9:S689–S696
Cao Y, Liao C, Tan A, Gao Y, Mo Z, Gao F. Meta-analysis of endoscopic submucosal dissection versus endoscopic mucosal resection for tumors of the gastrointestinal tract. Endoscopy. 2009; 41:751–757
Kanzaki H, Ishihara R, Ohta T, Nagai K, Matsui F, Yamashina T, et al. Randomized study of two endo-knives for endoscopic submucosal dissection of esophageal cancer. Am J Gastroenterol. 2013; 108:1293–1298
Takahashi H, Arimura Y, Masao H, Okahara S, Tanuma T, Kodaira J, et al. Endoscopic submucosal dissection is superior to conventional endoscopic resection as a curative treatment for early squamous cell carcinoma of the esophagus (with video). Gastrointest Endosc. 2010; 72:255–64, 264.e1
Kim JS, Kim BW, Shin IS. Efficacy and safety of endoscopic submucosal dissection for superficial squamous esophageal neoplasia: a meta-analysis. Dig Dis Sci. 2014; 59:1862–1869
Sooltangos A, Davenport M, McGrath S, Vickers J, Senapati S, Akhtar K, et al. Gastric endoscopic submucosal dissection as a treatment for early neoplasia and for accurate staging of early cancers in a United Kingdom Caucasian population. World J Gastrointest Endosc. 2017; 9:561–570
Pimentel-Nunes P, Dinis-Ribeiro M, Ponchon T, Repici A, Vieth M, De Ceglie A, et al. Endoscopic submucosal dissection: European Society of Gastrointestinal Endoscopy (ESGE) guideline. Endoscopy. 2015; 47:829–854
Participants in the Paris Workshop. The Paris endoscopic classification of superficial neoplastic lesions: esophagus, stomach, and colon. Am Soc Gastrointest Endosc. 2003; 58S6S3–S43
Ning B, Abdelfatah MM, Othman MO. Endoscopic submucosal dissection and endoscopic mucosal resection for early stage esophageal cancer. Ann Cardiothorac Surg. 2017; 6:88–98
Kandiah K, Chedgy FJ, Subramaniam S, Thayalasekaran S, Kurup A, Bhandari P. Early squamous neoplasia of the esophagus: the endoscopic approach to diagnosis and management. Saudi J Gastroenterol. 2017; 23:75–81
Chiu PW, Teoh AY, To KF, Wong SK, Liu SY, Lam CC, et al. Endoscopic submucosal dissection (ESD) compared with gastrectomy for treatment of early gastric neoplasia: a retrospective cohort study. Surg Endosc. 2012; 26:3584–3591
Yoshinaga S, Oda I, Nonaka S, Kushima R, Saito Y. Endoscopic ultrasound using ultrasound probes for the diagnosis of early esophageal and gastric cancers. World J Gastrointest Endosc. 2012; 4:218–226
Hull MJ, Mino-Kenudson M, Nishioka NS, Ban S, Sepehr A, Puricelli W, et al. Endoscopic mucosal resection: an improved diagnostic procedure for early gastroesophageal epithelial neoplasms. Am J Surg Pathol. 2006; 30:114–118
Lee IS, Park YS, Lee JH, Park JY, Kim HS, Kim BS, et al. Pathologic discordance of differentiation between endoscopic biopsy and postoperative specimen in mucosal gastric adenocarcinomas. Ann Surg Oncol. 2013; 20:4231–4237
Peters FP, Brakenhoff KP, Curvers WL, Rosmolen WD, Fockens P, ten Kate FJ, et al. Histologic evaluation of resection specimens obtained at 293 endoscopic resections in Barrett’s esophagus. Gastrointest Endosc. 2008; 67:604–609
National Institute for Health and Clinical Excellence. Interventional procedure overview of endoscopic submucosal dissection of oesophageal dysplasia and neoplasia [internet] London NICE Guidel. 20101–39. https://www.nice.org.uk/guidance/ipg355/documents/endoscopic-submucosal-dissection-esd-of-oesophageal-dysplasia-and-neoplasia-overview2. [Last accessed 31 May 2018]
Probst A, Aust D, Märkl B, Anthuber M, Messmann H. Early esophageal cancer in Europe: endoscopic treatment by endoscopic submucosal dissection. Endoscopy. 2015; 47:113–121
Matsubara H, Ando N, Nemoto K, Yahagi N, Ozawa S, Kajiyama Y, et al. Japanese classification of esophageal cancer, 11th edition: part I. Esophagus. 2017; 14:1–36
Matsubara H, Ando N, Nemoto K, Yahagi N, Ozawa S, Kajiyama Y, et al. Japanese classification of esophageal cancer, 11th edition: part II and III. Esophagus. 2017; 14:37–65
Dixon MF. Gastrointestinal epithelial neoplasia: Vienna revisited. Gut. 2002; 51:130–131
Kato H, Haga S, Endo S, Hashimoto M, Katsube T, Oi I, et al. Lifting of lesions during endoscopic mucosal resection (EMR) of early colorectal cancer: implications for the assessment of resectability. Endoscopy. 2001; 33:568–573
National Institute for Health and Care Excellence. Preoperative tests (update): routine preoperative tests for elective surgery [internet] London NICE Guidel. 201621. https://www.nice.org.uk/guidance/ng45/evidence/full-guideline-87258149468. [Last accessed 31 May 2018]
Ciocirlan M, Lapalus MG, Hervieu V, Souquet JC, Napoléon B, Scoazec JY, et al. Endoscopic mucosal resection for squamous premalignant and early malignant lesions of the esophagus. Endoscopy. 2007; 39:24–29
Park JS, Youn YH, Park JJ, Kim JH, Park H. Clinical outcomes of endoscopic submucosal dissection for superficial esophageal squamous neoplasms. Clin Endosc. 2016; 49:168–175
Tsujii Y, Nishida T, Nishiyama O, Yamamoto K, Kawai N, Yamaguchi S, et al. Clinical outcomes of endoscopic submucosal dissection for superficial esophageal neoplasms: a multicenter retrospective cohort study. Endoscopy. 2015; 47:775–783
Maynard M, Chadwick G, Varagunam M, Brand C, Cromwell D, Riley S, et al. National oesophago-gastric cancer audit 2017 [internet] R. Coll. Surg. Engl. 2017; 9:10–24. https://www.nogca.org.uk/content/uploads/2017/12/NOGCA-Annual-Report-2017.pdf. [Last accessed date 31 May 2018]
Tachimori Y, Ozawa S, Numasaki H, Ishihara R, Matsubara H, Muro K, et al.; Registration Committee for Esophageal Cancer of the Japan Esophageal Society. Comprehensive registry of esophageal cancer in Japan, 2011. Esophagus. 2018; 15:127–152
Tachibana M, Kinugasa S, Shibakita M, Tonomoto Y, Hattori S, Hyakudomi R, et al. Surgical treatment of superficial esophageal cancer Langenbecks Arch Surg. 2006; 391:304–321
Fujita H, Sueyoshi S, Yamana H, Shinozaki K, Toh U, Tanaka Y, et al. Optimum treatment strategy for superficial esophageal cancer: endoscopic mucosal resection versus radical esophagectomy World J Surg. 2001; 25:424–431
Yoshii T, Ohkawa S, Tamai S, Kameda Y. Clinical outcome of endoscopic mucosal resection for esophageal squamous cell cancer invading muscularis mucosa and submucosal layer. Dis Esophagus. 2013; 26:496–502
Yamashita T, Zeniya A, Ishii H, Tsuji T, Tsuda S, Nakane K, Komatsu M. Endoscopic mucosal resection using a cap-fitted panendoscope and endoscopic submucosal dissection as optimal endoscopic procedures for superficial esophageal carcinoma. Surg Endosc. 2011; 25:2541–2546