African Horse Sickness Fever in Vaccinated Horses: Short Communication.
African horse sickness fever
Laboratory investigation during outbreak
Journal
Journal of equine veterinary science
ISSN: 0737-0806
Titre abrégé: J Equine Vet Sci
Pays: United States
ID NLM: 8216840
Informations de publication
Date de publication:
05 2020
05 2020
Historique:
received:
06
01
2020
revised:
13
02
2020
accepted:
14
02
2020
entrez:
19
4
2020
pubmed:
19
4
2020
medline:
23
1
2021
Statut:
ppublish
Résumé
Our investigation has shown that multiple vaccinations with inactivated African horse sickness (AHS) vaccines containing all 9 serotypes and produced at the Central Veterinary Research Laboratory in Dubai, UAE, protect horses from AHS. However, the immunization did not prevent African horse sickness fever (AHSF) in approximately 10% of the vaccinated horses despite high enzyme-linked immunosorbent assay and virus neutralizing antibodies. African horse sickness fever is a very mild form of AHS with similar clinical signs. From all 6 horses which had developed AHSF, no virus was isolated from EDTA blood withdrawn during the acute phase of infection. Despite high neutralizing antibodies, serotype 9 was detected by polymerase chain reaction in 4 of them. All 6 horses recovered within 72 hours, after they developed mild clinical signs of AHS.
Identifiants
pubmed: 32303305
pii: S0737-0806(20)30058-7
doi: 10.1016/j.jevs.2020.102967
pii:
doi:
Substances chimiques
Antibodies, Neutralizing
0
Antibodies, Viral
0
Viral Vaccines
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
102967Informations de copyright
Copyright © 2020 Elsevier Inc. All rights reserved.