Multicenter evaluation of analytical performances of platelet counts and platelet parameters: Carryover, precision, and stability.
MPV
Platelets
automated counts
hematology analyzers
immature platelet fraction
Journal
International journal of laboratory hematology
ISSN: 1751-553X
Titre abrégé: Int J Lab Hematol
Pays: England
ID NLM: 101300213
Informations de publication
Date de publication:
Oct 2020
Oct 2020
Historique:
received:
17
11
2019
revised:
23
03
2020
accepted:
25
03
2020
pubmed:
19
4
2020
medline:
9
2
2021
entrez:
19
4
2020
Statut:
ppublish
Résumé
The correctness of the results of automated platelet analysis is still highly debated. The aim of this multicenter study, conducted according to international guidelines, was to verify the analytical performance of nine different types of hematology analyzers (HAs) in the automated platelet analysis. Four hundred eighty-six peripheral blood samples (PB), collected in K The carryover was absent for all HAs. The LoQ of PLT ranged between 2.0 (Cell-Dyn Sapphire) and 25.0 × 10 The findings of this study may provide useful information regarding carryover, precision, and stability of platelet counts and parameters, especially in thrombocytopenic samples. Moreover, the stability of sample for platelet analysis is conditioned by the HA and by temperature and storage time.
Types de publication
Journal Article
Multicenter Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
552-564Informations de copyright
© 2020 John Wiley & Sons Ltd.
Références
Lecompte TP, Bernimoulin MP. Novel parameters in blood cell counters. Clin Lab Med. 2015;35:209-224.
Buttarello M, Plebani M. Automated blood cell counts state of the art. Am J Clin Pathol. 2008;130:104-116.
Briggs C. Quality counts: new parameters in blood cell counting. Int J Lab Hematol. 2009;31:277-297.
Briggs C, Harrison P, Machin SJ. Continuing developments with the automated platelet count. Int J Lab Hematol. 2007;29:77-91.
Briggs C, Kunka S, Hart D, et al. Assessment of an immature platelet fraction (IPF) in peripheral thrombocytopenia. Br J Haematol. 2004;126:93-99.
Buoro S, Lippi G. Harmonization of laboratory hematology: a long and winding journey. Clin Chem Lab Med. 2018;56:1575-1578.
Noris P, Melazzini F, Balduini CL. New roles for mean platelet volume measurement in the clinical practice? Platelets. 2016;27:607-612.
Harrison P, Goodall HA. Studies on Mean Platelet Volume (MPV) - new editorial policy. Platelets. 2016;27:605-606.
Yuri Gasparyan A, Ayvazyan L, P. Mikhailidis D, et al. Mean platelet volume: a link between thrombosis and inflammation? Curr Pharm Des. 2011;17:47-58.
Noris P, Klersy C, Gresele P, et al. Platelet size for distinguishing between inherited thrombocytopenias and immune thrombocytopenia: a multicentric, real life study. Br J Haematol. 2013;162:112-119.
Chu SG, Becker RC, Berger PB, et al. Mean platelet volume as a predictor of cardiovascular risk: a systematic review and metaanalysis. J Thromb Haemost. 2010;8:148-156.
Machin SJ, Briggs C. Mean platelet volume: a quick, easy determinant of thrombotic risk? J Thromb Haemost. 2010;8:146-147.
Lancé MD, Sloep M, Henskens YMC, et al. Mean platelet volume as a diagnostic marker for cardiovascular disease: drawbacks of preanalytical conditions and measuring techniques. Clin Appl Thromb Hemost. 2012;18:561-568.
Daves M, Zagler EM, Cemin R, et al. Sample stability for complete blood cell count using the Sysmex XN haematological analyser. Blood Transfus. 2015;13:576-582.
Zandecki M, Genevieve F, Gerard J, et al. Spurious counts and spurious results on haematology analysers: a review. Part I: platelets. Int J Lab Hematol. 2007;29:4-20.
Hoffmann JJML. Reticulated platelets: analytical aspects and clinical utility. Clin Chem Lab Med. 2014;52:1107-1117.
Park SH, Ha SO, Cho Y-U, et al. Immature platelet fraction in septic patients: clinical relevance of immature platelet fraction is limited to the sensitive and accurate discrimination of septic patients from non-septic patients, not to the discrimination of sepsis severity. Ann Lab Med. 2016;36:1-8.
Gilberti M, de Castro V, Annichino-Bizzacchi JM, et al. Association of the immature platelet fraction with sepsis diagnosis and severity. Sci Rep. 2015;26:1-6.
Buoro S, Manenti B, Seghezzi M, et al. Innovative haematological parameters for early diagnosis of sepsis in adult patients admitted in intensive care unit. J Clin Pathol. 2018;71:330-335.
Stratz C, Bömicke T, Younas I, et al. Comparison of immature platelet count to established predictors of platelet reactivity during thienopyridine therapy. Am Coll Cardiol. 2016;68:286-293.
Panasiuk A, Prokopowicz D, Zak J, et al. Reticulated platelets as a marker of megakaryopoiesis in liver cirrhosis; relation to thrombopoietin and hepatocyte growth factor serum concentration. Hepatogastroenterology. 2004;51:1124-1128.
Saigo K, Takenokuchi M, Imai J, et al. Usefulness of immature platelet fraction for the clinical evaluation of myelodysplastic syndromes. Lab Hematol. 2009;15:13-16.
Kim SY, Kim J-E, Kim HK, et al. Accuracy of platelet counting by automated hematologic analyzers in acute leukemia and disseminated intravascular coagulation: potential effects of platelet activation. Am J Clin Pathol. 2010;134:634-647.
Norris S, Pantelidou D, Smith D, et al. Immunoplatelet counting: potential for reducing the use of platelet transfusions through more accurate platelet counting. Br J Haematol. 2003;121:605-613.
Segal HC, Briggs C, Kunka S, et al. Accuracy of platelet counting haematology analysers in severe thrombocytopenia and potential impact on platelet transfusion. Br J Haematol. 2005;128:520-525.
De la Salle BJ, McTaggart PN, Briggs C, et al. The accuracy of platelet counting in thrombocytopenic blood samples distributed by the UK National External Quality Assessment Scheme for General Haematology. Am J Clin Pathol. 2012;137:65-74.
Briggs C, Culp N, Davis B, et al. ICSH guidelines for the evaluation of blood cell analysers including those used for differential leucocyte and reticulocyte counting. Int J Lab Hematol. 2014;36:613-627.
CLSI Document H26-A2. Validation, Verification, and Quality Assurance of Automated Hematology Analyzers, 2nd ed. Wayne, PA: Clinical and Laboratory Standard Institute; 2010.
CLSI document EP5-A3. Evaluation of Precision of Quantitative Measurement Procedures; Approved Guideline-Third Edition. Wayne, PA: Clinical and Laboratory Standard Institute; 2014.
Buoro S, Seghezzi M, Manenti B, et al. Biological variation of platelet parameters determined by the Sysmex XN hematology analyzer. Clin Chim Acta. 2017;470:125-132.
Vis JY, Huisman A. Verification and quality control of routine hematology analyzers. Int J Lab Hematol. 2016;38:100-109.
Schmidt AE, Refaai MA, Blumberg N. Platelet transfusion and thrombosis: more questions than answers. Semin Thromb Hemost. 2016;42:118-124.
Birindelli S, Aloisio E, Carnevale A, et al. Evaluation of long-term imprecision of automated complete blood cell count on the Sysmex XN-9000 system. Clin Chem Lab Med. 2017;55(10):e219-e222.
Buoro S, Mecca T, Seghezzi M, et al. Assessment of blood sample stability for complete blood count using the Sysmex XN-9000 and Mindray BC-6800 analyzers. Rev Bras Hematol Hemoter. 2016;38:225-239.
International Council for Standardization in Haematology Expert Panel on Cytometry, International Society of Laboratory Hematology Task Force on Platelet Counting. Platelet counting by the RBC/platelet ratio method. A reference method. Am J Clin Pathol. 2001;115:460-464.
Lippi G, Favaloro EJ, Buoro S. Platelet transfusion thresholds: how low can we go in respect to platelet counting? Semin Thromb Hemost. 2019. https://doi.org/10.1055/s-0039-1696943