Globe Axial Length Growth at Age 10.5 Years in the Infant Aphakia Treatment Study.
Journal
American journal of ophthalmology
ISSN: 1879-1891
Titre abrégé: Am J Ophthalmol
Pays: United States
ID NLM: 0370500
Informations de publication
Date de publication:
08 2020
08 2020
Historique:
received:
07
11
2019
revised:
06
04
2020
accepted:
07
04
2020
pubmed:
19
4
2020
medline:
3
10
2020
entrez:
19
4
2020
Statut:
ppublish
Résumé
To report the change in globe axial length (AL) from the time of unilateral cataract surgery at age 1-7 months to age 10.5 years for infants enrolled in the Infant Aphakia Treatment Study, and to compare AL growth of operated eyes with that of fellow unoperated eyes. Comparative case series. AL growth was analyzed relative to treated vs fellow eye, contact lens (CL) vs intraocular lens (IOL), visual acuity (VA) outcome, and the need for surgery for visual axis opacification. Eyes with glaucoma or glaucoma suspect were excluded from the primary analysis but reported separately. Fifty-seven patients have reliable AL data available at both visits. AL was shorter in treated eyes preoperatively (P < .0001) and at 10.5 years of age (P = .021) but AL growth was not different (4.7 mm, P = .99). The growth (70.2% up to age 5 and 29.8% from age 5 to 10.5) was similar in the CL and the IOL group (P = .79). Eyes grew 4.4 mm when visual acuity (VA) was better than 20/200, and 5.2 mm when VA was 20/200 or worse (P = .076). Eyes receiving additional surgery grew more than eyes not receiving additional surgery (P = .052). Patients with glaucoma showed significantly more eye growth (7.3 mm) than those without glaucoma (4.7 mm) and glaucoma suspects (5.1 mm) (P < .05). Eyes with glaucoma or poor VA often grew longer than the fellow eye. Overall, treated eyes grew similarly in the IOL and CL groups and also kept pace with the growth of the fellow eyes.
Identifiants
pubmed: 32304705
pii: S0002-9394(20)30178-1
doi: 10.1016/j.ajo.2020.04.010
pmc: PMC7593806
mid: NIHMS1585358
pii:
doi:
Types de publication
Comparative Study
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
147-155Subventions
Organisme : NEI NIH HHS
ID : P30 EY026877
Pays : United States
Organisme : NEI NIH HHS
ID : U10 EY013272
Pays : United States
Organisme : NEI NIH HHS
ID : U10 EY013287
Pays : United States
Organisme : NEI NIH HHS
ID : UG1 EY025553
Pays : United States
Organisme : NEI NIH HHS
ID : UG1 EY013272
Pays : United States
Informations de copyright
Copyright © 2020 Elsevier Inc. All rights reserved.
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