Predictors of live birth rate in women with diminished ovarian reserve.
Bologna criteria
Diminished ovarian reserve
In vitro fertilization
Live birth rate
Poor ovarian response
Journal
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
ISSN: 1879-3479
Titre abrégé: Int J Gynaecol Obstet
Pays: United States
ID NLM: 0210174
Informations de publication
Date de publication:
Aug 2020
Aug 2020
Historique:
received:
23
09
2019
revised:
20
02
2020
accepted:
15
04
2020
pubmed:
20
4
2020
medline:
5
11
2020
entrez:
20
4
2020
Statut:
ppublish
Résumé
To investigate the chance of live birth after several oocyte retrieval cycles in patients with diminished ovarian reserve (DOR) and identify the possible predictors. A retrospective analysis of 931 patients with DOR who underwent in vitro fertilization at a university hospital in China between January 2012 and December 2014. All data for fresh and the associated frozen-thawed embryo transfer attempts were analyzed. Conditional and cumulative live birth rates (LBRs) were calculated. Mediation and logistic regression analyses were performed to determine the predictors of live birth. Conditional LBRs remained around 10.0% in the first five cycles. Conservative cumulative LBRs (CLBRs) reached 22.0% after three cycles and increased to 24.8% after six cycles; optimal CLBRs increased from 12.9% to nearly 50.0% after six cycles. Patient age and the number of good-quality embryos were two key predictors in determining the conditional and conservative LBRs. For patients with DOR, conditional LBR remained constant in the first five cycles, and patients should be encouraged to continue to three or five completed cycles to maximize their chance of live birth. Patient age and the number of good-quality embryos were two key factors to predict live birth.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
222-227Subventions
Organisme : National Key Research and Development Program of China
Organisme : National Natural Science Foundation of China
Informations de copyright
© 2020 International Federation of Gynecology and Obstetrics.
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