Different MAF translocations confer similar prognosis in newly diagnosed multiple myeloma patients.

Disease-Free Survival Hematopoietic Stem Cell Transplantation Humans Multiple Myeloma / diagnosis Prognosis Retrospective Studies Transplantation, Autologous Treatment Outcome
MAF Translocation myeloma survival t(14;16) t(14;20)

Journal

Leukemia & lymphoma
ISSN: 1029-2403
Titre abrégé: Leuk Lymphoma
Pays: United States
ID NLM: 9007422

Informations de publication

Date de publication:
08 2020
Historique:
pubmed: 21 4 2020
medline: 28 4 2021
entrez: 21 4 2020
Statut: ppublish

Résumé

The MAF translocations, t(14;16) and t(14;20), are considered as adverse prognostic factors based on few studies with small sample sizes. We report on their prognostic impact in a large group of 254 patients - 223 (87.8%) with t(14;16) and 31 (12.2%) with t(14;20). There were no intergroup differences in survival estimates. Median progression-free survival was 16.6 months for t(14;16) and 24.9 months for t(14;20) (

Identifiants

DOI: 10.1080/10428194.2020.1749605 PMID: 32306794
pubmed: 32306794
doi: 10.1080/10428194.2020.1749605
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1885-1893

Auteurs

Sarah Goldman-Mazur (S)

Department of Hematology, Jagiellonian University Medical College, Cracow, Poland.

Artur Jurczyszyn (A)

Department of Hematology, Jagiellonian University Medical College, Cracow, Poland.

Jorge J Castillo (JJ)

Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
ORCID: 0000-0001-9490-7532

Anna Waszczuk-Gajda (A)

Department of Hematology, Oncology and Internal Diseases, Warsaw Medical University, Warsaw, Poland.
ORCID: 0000-0001-5626-1750

Norbert Grząśko (N)

Department of Experimental Hematology, Medical University of Lublin, Lublin, Poland.
Department of Hematology, St. John's Cancer Center, Lublin, Poland.

Jakub Radocha (J)

4th Department of Internal Medicine - Hematology, University Hospital, Faculty of Medicine in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic.

Max Bittrich (M)

Department of Internal Medicine II, University Hospital Würzburg, Würzburg, Germany.

Klaus Martin Kortüm (KM)

Department of Internal Medicine II, University Hospital Würzburg, Würzburg, Germany.
ORCID: 0000-0002-7011-0286

Alessandro Gozzetti (A)

Division of Hematology, Department of Medical Science, Surgery and Neuroscience, University of Siena, Siena, Italy.

Lidia Usnarska-Zubkiewicz (L)

Department of Hematology, Wroclaw Medical University, Wroclaw, Poland.

Julio D Valls (JD)

Complejo Asistencial de Avila, Avila, Spain.

David S Jayabalan (DS)

Weill Cornell Medical College, New York, NY, USA.

Ruben Niesvizky (R)

Weill Cornell Medical College, New York, NY, USA.

Julia Kelman (J)

Weill Cornell Medical College, New York, NY, USA.

Daniel Coriu (D)

Department of Hematology, Fundeni Clinical Institute, University of Medicine and Pharmacy "Carol Davila", Bucharest, Romania.
ORCID: 0000-0002-7251-6079

Laura Rosiñol (L)

Departments of Hematology, Amyloidosis and Myeloma Unit, Hospital Clínic, IDIBAPS, University of Barcelona, Barcelona, Spain.
ORCID: 0000-0001-9531-961X

Łukasz Szukalski (Ł)

Department of Hematology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University, Toruń, Poland.

Veronica González-Calle (V)

Hospital Universitario de Salamanca/Instituto Biosanitario de Salamanca (IBSAL), Salamanca, Spain.

María-Victoria Mateos (MV)

Hospital Universitario de Salamanca/Instituto Biosanitario de Salamanca (IBSAL), Salamanca, Spain.
ORCID: 0000-0003-2390-1218

Krzysztof Jamroziak (K)

Institute of Hematology and Transfusion Medicine, Warsaw, Poland.

Iwona Hus (I)

Department of Experimental Hematology, Medical University of Lublin, Lublin, Poland.
Department of Hematology, St. John's Cancer Center, Lublin, Poland.
Institute of Hematology and Transfusion Medicine, Warsaw, Poland.

Irit Avivi (I)

Tel Aviv Sourasky Medical Center, Tel Aviv, Israel and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Yael Cohen (Y)

Tel Aviv Sourasky Medical Center, Tel Aviv, Israel and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
ORCID: 0000-0002-9061-7287

Piotr Mazur (P)

Institute of Cardiology, Jagiellonian University Medical College, Cracow, Poland.
ORCID: 0000-0003-4077-1232

Anna Suska (A)

Department of Hematology, Jagiellonian University Medical College, Cracow, Poland.

Aimee Chappell (A)

Department of Hematology/Oncology, Medstar Georgetown University Hospital, Washington, NW, USA.

Deepu Madduri (D)

Icahn School of Medicine at Mount Sinai, Tisch Cancer Institute, New York, NY, USA.

Saurabh Chhabra (S)

Division of Hematology/Oncology, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA.

Ariel Kleman (A)

Division of Hematology/Oncology, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA.

Parameswaran Hari (P)

Division of Hematology/Oncology, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA.

Michel Delforge (M)

Department of Hematology, UZ Leuven, Leuven, Belgium.

Paweł Robak (P)

Department of Experimental Hematology, Medical University of Lodz, Lodz, Poland.

Massimo Gentile (M)

Hematology Unit, AO Cosenza, Cosenza, Italy.

Izabela Kozłowska (I)

Department of Hematology, SPZOZ ZSM, Chorzow, Poland.

Stuart L Goldberg (SL)

John Theurer Cancer Center, Hackensack UMC, Hackensack, NJ, USA.
Cota Inc, Boston, MA, USA.

Jacek Czepiel (J)

Department of Infectious and Tropical Diseases, Jagiellonian University Medical College, Cracow, Poland.

Monika Długosz-Danecka (M)

Maria Sklodowska-Curie National Institute of Oncology, Cracow, Poland.
ORCID: 0000-0002-8927-4125

Rebecca Silbermann (R)

Division of Hematology and Medical Oncology, Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA.

Adam J Olszewski (AJ)

Department of Medicine, Warren Alpert Medical School, Brown University, Providence, RI, USA.
ORCID: 0000-0002-6472-6658

Peter Barth (P)

Department of Medicine, Warren Alpert Medical School, Brown University, Providence, RI, USA.

Gabor Mikala (G)

Department of Hematology and Stem Cell Transplantation, South-Pest Central Hospital, National Institute of Hematology and Infectology, Budapest, Hungary.

Chor S Chim (CS)

Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong, Hong Kong.
ORCID: 0000-0003-2427-915X

David H Vesole (DH)

John Theurer Cancer Center, Hackensack UMC, Hackensack, NJ, USA.

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Classifications MeSH

questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Analyse de survie › Survie sans rechute › Different MAF translocations confer similar...
questionsmedicales.fr › Procédures de chirurgie opératoire › Transplantation › Transplantation cellulaire › Transplantation de cellules souches › Transplantation de cellules souches hématopoïétiques › Different MAF translocations confer similar...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Different MAF translocations confer similar...
questionsmedicales.fr › Maladies du système immunitaire › Syndromes immunoprolifératifs › Paraprotéinémies › Myélome multiple › Different MAF translocations confer similar...
questionsmedicales.fr › Diagnostic › Pronostic › Different MAF translocations confer similar...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Études rétrospectives › Different MAF translocations confer similar...
questionsmedicales.fr › Procédures de chirurgie opératoire › Transplantation › Transplantation autologue › Different MAF translocations confer similar...
questionsmedicales.fr › Qualité, accès, évaluation des soins de santé › Qualité des soins de santé › Mécanismes d'évaluation des soins de santé › Évaluation des résultats et des processus en soins de santé › Évaluation de résultat (soins) › Résultat thérapeutique › Different MAF translocations confer similar...