Association of abdominal fat with metabolic syndrome components in overweight women: effect of menopausal status.
Abdominal deep subcutaneous fat
Abdominal superficial subcutaneous fat
Menopause
Journal
Journal of physiological anthropology
ISSN: 1880-6805
Titre abrégé: J Physiol Anthropol
Pays: England
ID NLM: 101269653
Informations de publication
Date de publication:
19 Apr 2020
19 Apr 2020
Historique:
received:
04
02
2020
accepted:
06
04
2020
entrez:
21
4
2020
pubmed:
21
4
2020
medline:
11
11
2020
Statut:
epublish
Résumé
The association between abdominal fat distribution and metabolic syndrome (MetSyn) components by menopausal status has yet to be explicated. The purpose of this study was to examine a cross-sectional association between abdominal fat compartments and MetSyn components in pre- and post-menopausal overweight Japanese women. Of 212 overweight Japanese women, 76 pre-menopausal overweight (BMI ≥ 25) women (PreM age, 42.1 ± 5.9 years) and 87 post-menopausal overweight women (PostM: age, 56.2 ± 4.5 years) were analyzed in this study. Measurements were taken for body mass index (BMI), abdominal compartments [visceral fat (VF), subcutaneous fat (SF), superficial subcutaneous fat (SSF), and deep subcutaneous fat (DSF)], serum high-density lipoprotein cholesterol (HDLC), low-density lipoprotein cholesterol, triglycerides (TG), and fasting plasma glucose (FPG). Abdominal compartments were assessed using computed tomography. No significant differences were found for BMI, SF, SSF, or DSF between the PreM and PostM. Despite this, the PreM had a significantly smaller VF area than that of the PostM. However, the difference in VF area disappeared when age was adjusted for. VFA significantly correlated with HDLC, TG, and FPG independently of menopause status. These results suggest that the effect of menopause status on the association between VF and MetSyn components is negligible. Abdominal subcutaneous fat compartments were not associated with MetSyn components in overweight women regardless of menopausal status.
Sections du résumé
BACKGROUND
BACKGROUND
The association between abdominal fat distribution and metabolic syndrome (MetSyn) components by menopausal status has yet to be explicated. The purpose of this study was to examine a cross-sectional association between abdominal fat compartments and MetSyn components in pre- and post-menopausal overweight Japanese women.
METHODS
METHODS
Of 212 overweight Japanese women, 76 pre-menopausal overweight (BMI ≥ 25) women (PreM age, 42.1 ± 5.9 years) and 87 post-menopausal overweight women (PostM: age, 56.2 ± 4.5 years) were analyzed in this study. Measurements were taken for body mass index (BMI), abdominal compartments [visceral fat (VF), subcutaneous fat (SF), superficial subcutaneous fat (SSF), and deep subcutaneous fat (DSF)], serum high-density lipoprotein cholesterol (HDLC), low-density lipoprotein cholesterol, triglycerides (TG), and fasting plasma glucose (FPG). Abdominal compartments were assessed using computed tomography.
RESULTS
RESULTS
No significant differences were found for BMI, SF, SSF, or DSF between the PreM and PostM. Despite this, the PreM had a significantly smaller VF area than that of the PostM. However, the difference in VF area disappeared when age was adjusted for. VFA significantly correlated with HDLC, TG, and FPG independently of menopause status.
CONCLUSIONS
CONCLUSIONS
These results suggest that the effect of menopause status on the association between VF and MetSyn components is negligible. Abdominal subcutaneous fat compartments were not associated with MetSyn components in overweight women regardless of menopausal status.
Identifiants
pubmed: 32307016
doi: 10.1186/s40101-020-00222-0
pii: 10.1186/s40101-020-00222-0
pmc: PMC7168819
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
12Subventions
Organisme : The 21st century COE (Center of Excellence) program (2002-2003 Nishihira/Tsukuba Project: Promotion of health and sport scientific research), Japan, Ministry of Education, Culture, Sports, Science and Technology
ID : E02
Références
Lancet. 2004 Jan 10;363(9403):157-63
pubmed: 14726171
Arterioscler Thromb Vasc Biol. 2004 May;24(5):923-9
pubmed: 15016639
Cancer Causes Control. 2011 Apr;22(4):581-8
pubmed: 21287259
Circulation. 2009 Oct 20;120(16):1640-5
pubmed: 19805654
Nutr Rev. 1988 Feb;46(2):79-82
pubmed: 2894629
Menopause. 2002 Nov-Dec;9(6):456-62
pubmed: 12439106
Asia Pac J Clin Nutr. 2001;10(2):85-9
pubmed: 11710363
Endocr J. 2002 Aug;49(4):503-9
pubmed: 12402983
Menopause. 2019 Nov;26(11):1327-1333
pubmed: 31567869
J Clin Endocrinol Metab. 2003 Apr;88(4):1516-22
pubmed: 12679432
Metabolism. 2001 Apr;50(4):425-35
pubmed: 11288037
Am J Obstet Gynecol. 2019 Nov;221(5):393-409.e50
pubmed: 31034807
Radiology. 1999 Apr;211(1):283-6
pubmed: 10189485
Obes Res. 2002 Apr;10(4):266-9
pubmed: 11943835
Diabetes Care. 2004 Jul;27(7):1699-705
pubmed: 15220249
Int J Obes (Lond). 2007 Jun;31(6):933-41
pubmed: 17264848
Ann N Y Acad Sci. 1963 Sep 26;110:113-40
pubmed: 14062375
Am J Physiol Endocrinol Metab. 2001 Nov;281(5):E1110-4
pubmed: 11595670
J Clin Invest. 1995 Jul;96(1):88-98
pubmed: 7615840
J Clin Endocrinol Metab. 2012 Apr;97(4):1159-68
pubmed: 22344196
Am J Physiol Endocrinol Metab. 2002 Dec;283(6):E1135-43
pubmed: 12424102
Int J Obes (Lond). 2008 Jun;32(6):949-58
pubmed: 18332882
Circ J. 2014;78(5):1259-63
pubmed: 24621566
Am J Obstet Gynecol. 1996 Dec;175(6):1594-600
pubmed: 8987946
Int J Obes Relat Metab Disord. 2000 Feb;24(2):226-31
pubmed: 10702775
Cancer Causes Control. 2001 Jan;12(1):47-59
pubmed: 11227925
J Clin Epidemiol. 2001 Feb;54(2):117-20
pubmed: 11166525
Metabolism. 1996 Sep;45(9):1119-24
pubmed: 8781299
J Gerontol A Biol Sci Med Sci. 2003 Feb;58(2):181-9
pubmed: 12586858
Int J Obes Relat Metab Disord. 1994 Apr;18(4):207-2
pubmed: 8044194
Obes Res. 2002 Jun;10(6):424-31
pubmed: 12055317
Int J Obes Relat Metab Disord. 1992 Jul;16(7):495-504
pubmed: 1323546
Circulation. 2007 Jul 3;116(1):39-48
pubmed: 17576866
Am J Physiol Endocrinol Metab. 2000 May;278(5):E941-8
pubmed: 10780952
Obes Res. 2003 Mar;11(3):469-76
pubmed: 12634447
Am J Physiol Endocrinol Metab. 2001 Jul;281(1):E113-21
pubmed: 11404228
Acta Diabetol. 2003 Oct;40 Suppl 1:S302-4
pubmed: 14618500
Obes Res. 2001 Jan;9(1):10-6
pubmed: 11346662