A quickly, effectively screening process of novel corona virus disease 2019 (COVID-19) in children in Shanghai, China.

Corona virus disease 2019 (COVID-19) child diagnosis severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Journal

Annals of translational medicine
ISSN: 2305-5839
Titre abrégé: Ann Transl Med
Pays: China
ID NLM: 101617978

Informations de publication

Date de publication:
Mar 2020
Historique:
entrez: 21 4 2020
pubmed: 21 4 2020
medline: 21 4 2020
Statut: ppublish

Résumé

A recent cluster of pneumonia cases in China was caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We report the screening and diagnosis of corona virus disease 2019 (COVID-19) in our hospital. Developed a procedure for the identification of children cases with COVID-19 in outpatient and emergency department of our hospital, then we observed how this process works. (I) There were 56 cases considered suspected cases, and 10 cases were confirmed as COVID-19. (II) Of the 10 confirmed COVID-19 cases admitted in our hospital, 5 were males and 5 were females, aged from 7 months to 11 years, the average age is 6.0±4.2 years, 6 cases were mild pneumonia, the others were upper respiratory tract infection. (III) We followed up 68 patients in isolation at home until symptoms disappeared. Non were missed in the patient's first visit. The sensitivity of this method is 100% and the specificity is 71.3%. Our screening process works well, and it is also necessary to establish a screening network in the hospital.

Sections du résumé

BACKGROUND BACKGROUND
A recent cluster of pneumonia cases in China was caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We report the screening and diagnosis of corona virus disease 2019 (COVID-19) in our hospital.
METHODS METHODS
Developed a procedure for the identification of children cases with COVID-19 in outpatient and emergency department of our hospital, then we observed how this process works.
RESULTS RESULTS
(I) There were 56 cases considered suspected cases, and 10 cases were confirmed as COVID-19. (II) Of the 10 confirmed COVID-19 cases admitted in our hospital, 5 were males and 5 were females, aged from 7 months to 11 years, the average age is 6.0±4.2 years, 6 cases were mild pneumonia, the others were upper respiratory tract infection. (III) We followed up 68 patients in isolation at home until symptoms disappeared. Non were missed in the patient's first visit. The sensitivity of this method is 100% and the specificity is 71.3%.
CONCLUSIONS CONCLUSIONS
Our screening process works well, and it is also necessary to establish a screening network in the hospital.

Identifiants

pubmed: 32309388
doi: 10.21037/atm.2020.03.22
pii: atm-08-05-241
pmc: PMC7154461
doi:

Types de publication

Journal Article

Langues

eng

Pagination

241

Informations de copyright

2020 Annals of Translational Medicine. All rights reserved.

Déclaration de conflit d'intérêts

Conflicts of Interest: The authors have no conflicts of interest to declare.

Références

Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):13116-21
pubmed: 18725624
Science. 2005 Jan 28;307(5709):580-4
pubmed: 15681385
N Engl J Med. 2020 Mar 26;382(13):1199-1207
pubmed: 31995857
N Engl J Med. 2020 Feb 20;382(8):727-733
pubmed: 31978945
J Family Med Prim Care. 2019 Feb;8(2):455-461
pubmed: 30984654
Viruses. 2020 Jan 24;12(2):
pubmed: 31991541
J Med Virol. 2020 Apr;92(4):418-423
pubmed: 31967327
J Med Virol. 2020 Apr;92(4):441-447
pubmed: 31994742
Lancet. 2020 Feb 15;395(10223):497-506
pubmed: 31986264
mBio. 2020 Jan 21;11(1):
pubmed: 31964741
Transl Pediatr. 2020 Feb;9(1):51-60
pubmed: 32154135
Euro Surveill. 2020 Jan;25(3):
pubmed: 31992390

Auteurs

Yu Shi (Y)

Division of Medical Administration, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.

Xiangshi Wang (X)

Department of Infectious Disease, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.

Gongbao Liu (G)

Division of Medical Administration, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.

Qirong Zhu (Q)

Department of Infectious Disease, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.

Jianshe Wang (J)

Department of Infectious Disease, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.

Hui Yu (H)

Department of Infectious Disease, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.

Chuanqing Wang (C)

Department of Hospital Infection Control, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.

Libo Wang (L)

Department of Respiration, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.

Mingzhi Zhang (M)

Department of Respiration, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.

Lingen Zhang (L)

Department of Critical Care Medicine, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.

Guoping Lu (G)

Department of Critical Care Medicine, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.

Zhujin Lu (Z)

Department of Critical Care Medicine, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.

Jian Yu (J)

Department of Traditional Chinese Medicine, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.

Zhongwei Qiao (Z)

Department of Medical Image, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.

Ying Gu (Y)

Department of Nursing, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.

Guomei Shen (G)

Outpatient and Emergency Management Office, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.

Hong Xu (H)

Department of Nephrology/Rheumatology, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.
Hospital Administration, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.

Mei Zeng (M)

Department of Infectious Disease, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.

Xiaowen Zhai (X)

Hospital Administration, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.
Department of Hematology/Oncology, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.

Guoying Huang (G)

Hospital Administration, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.
Heart Center, National Children's Medical Center, Children's Hospital of Fudan University, Shanghai 201102, China.

Classifications MeSH