Functional Results, Complications Associated with the Serosa-lined Tunnel, and Quality of Life with a Cross-folded Ileal Reservoir Combined with an Afferent Tubular Isoperistaltic Segment for Heterotopic Continent Urinary Diversion: An Observational Long-term Cohort Analysis.


Journal

European urology focus
ISSN: 2405-4569
Titre abrégé: Eur Urol Focus
Pays: Netherlands
ID NLM: 101665661

Informations de publication

Date de publication:
Jul 2021
Historique:
received: 28 01 2020
revised: 10 03 2020
accepted: 23 03 2020
pubmed: 23 4 2020
medline: 14 4 2022
entrez: 23 4 2020
Statut: ppublish

Résumé

In patients who do not qualify for an orthotopic urinary diversion, for example, the urethra cannot be spared or is functionally impaired, a heterotopic continent cutaneous cross-folded ileal reservoir offers a good alternative. To describe the indication, surgical technique, and postoperative management, and to report the reservoir-related outcomes and complications associated with the serosa-lined tunnel. Perioperative outcomes of 118 consecutive patients after cystectomy and a heterotopic ileal reservoir adapted from the Studer bladder substitute technique, operated between 2000 and 2018, were evaluated. The catheterisable serosa-lined tunnel was constructed from the appendix (Mitrofanoff, n = 63), an ileal segment (Yang-Monti, n = 48), or a fallopian tube (n = 7). Pre- and postoperative data until last follow-up appointment were entered prospectively in the departmental database. The chi-square test was used to compare proportions. Median follow-up was 94 (interquartile range 36-152) mo. No peri- or postoperative mortality was observed within 90 d of surgery. Patient satisfaction was high in 77.5% and moderate in 16.9%. Overall, complications associated with the serosa-lined tunnel occurred in 52% (61/118) of patients. Stenosis of the continent outlet developed in 38% (45/118) of patients: 33/45 (75%) were simply dilated/incised at the outpatient clinic, of those 24% (8/33) required additional endoscopic dilatation. Of patients with stenosis of the continent outlet, 27% (12/45) needed open revision surgery. During follow-up, 8% (nine/118) of patients required revision of the serosa-lined tunnel due to incontinence. Twelve months postoperatively, 95% (92/97) patients were continent. A limitation is the retrospective analysis from prospectively assessed data. This could limit the generalisability of these findings, as selection bias cannot be excluded. The heterotopic continent cutaneous cross-folded ileal reservoir achieves good functional results. Complications associated with the serosa-lined tunnel occur in about half of the patients but generally are easy to manage. As a result, patient satisfaction is high. In patients who do not qualify for an orthotopic bladder substitute, a heterotopic continent cutaneous cross-folded ileal reservoir offers a viable alternative with good postoperative functional results and high patient satisfaction.

Sections du résumé

BACKGROUND BACKGROUND
In patients who do not qualify for an orthotopic urinary diversion, for example, the urethra cannot be spared or is functionally impaired, a heterotopic continent cutaneous cross-folded ileal reservoir offers a good alternative.
OBJECTIVE OBJECTIVE
To describe the indication, surgical technique, and postoperative management, and to report the reservoir-related outcomes and complications associated with the serosa-lined tunnel.
DESIGN, SETTING, AND PARTICIPANTS METHODS
Perioperative outcomes of 118 consecutive patients after cystectomy and a heterotopic ileal reservoir adapted from the Studer bladder substitute technique, operated between 2000 and 2018, were evaluated. The catheterisable serosa-lined tunnel was constructed from the appendix (Mitrofanoff, n = 63), an ileal segment (Yang-Monti, n = 48), or a fallopian tube (n = 7).
OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS METHODS
Pre- and postoperative data until last follow-up appointment were entered prospectively in the departmental database. The chi-square test was used to compare proportions.
RESULTS AND LIMITATIONS CONCLUSIONS
Median follow-up was 94 (interquartile range 36-152) mo. No peri- or postoperative mortality was observed within 90 d of surgery. Patient satisfaction was high in 77.5% and moderate in 16.9%. Overall, complications associated with the serosa-lined tunnel occurred in 52% (61/118) of patients. Stenosis of the continent outlet developed in 38% (45/118) of patients: 33/45 (75%) were simply dilated/incised at the outpatient clinic, of those 24% (8/33) required additional endoscopic dilatation. Of patients with stenosis of the continent outlet, 27% (12/45) needed open revision surgery. During follow-up, 8% (nine/118) of patients required revision of the serosa-lined tunnel due to incontinence. Twelve months postoperatively, 95% (92/97) patients were continent. A limitation is the retrospective analysis from prospectively assessed data. This could limit the generalisability of these findings, as selection bias cannot be excluded.
CONCLUSIONS CONCLUSIONS
The heterotopic continent cutaneous cross-folded ileal reservoir achieves good functional results. Complications associated with the serosa-lined tunnel occur in about half of the patients but generally are easy to manage. As a result, patient satisfaction is high.
PATIENT SUMMARY RESULTS
In patients who do not qualify for an orthotopic bladder substitute, a heterotopic continent cutaneous cross-folded ileal reservoir offers a viable alternative with good postoperative functional results and high patient satisfaction.

Identifiants

pubmed: 32317156
pii: S2405-4569(20)30094-8
doi: 10.1016/j.euf.2020.03.006
pii:
doi:

Types de publication

Journal Article Observational Study Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

869-876

Informations de copyright

Copyright © 2020. Published by Elsevier B.V.

Auteurs

Marc A Furrer (MA)

Department of Urology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland; Departments of Surgery and Urology, The University of Melbourne, Royal Melbourne Hospital, Parkville, Victoria, Australia. Electronic address: marcalain.furrer@outlook.com.

Ladina Noser (L)

Department of Urology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

Benjamin Lyttwin (B)

Department of Urology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

Bernhard Kiss (B)

Department of Urology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

Benjamin C Thomas (BC)

Departments of Surgery and Urology, The University of Melbourne, Royal Melbourne Hospital, Parkville, Victoria, Australia.

Piet Bosshard (P)

Department of Urology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

Patrick Y Wüthrich (PY)

Department of Anaesthesiology and Pain Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

Urs E Studer (UE)

Department of Urology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

Fiona C Burkhard (FC)

Department of Urology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

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