Antibacterial activity of ethoxzolamide against

Ethoxzolamide Genome sequencing Mutation frequency Resistance

Journal

Gut pathogens
ISSN: 1757-4749
Titre abrégé: Gut Pathog
Pays: England
ID NLM: 101474263

Informations de publication

Date de publication:
2020
Historique:
received: 30 12 2019
accepted: 06 04 2020
entrez: 23 4 2020
pubmed: 23 4 2020
medline: 23 4 2020
Statut: epublish

Résumé

With the rise of bacterial resistance to conventional antibiotics, re-purposing of Food and Drug Administration (FDA) approved drugs currently used to treat non-bacteria related diseases as new leads for antibacterial drug discovery has become an attractive alternative. Ethoxzolamide (EZA), an FDA-approved diuretic acting as a human carbonic anhydrase inhibitor, is known to kill the gastric pathogenic bacterium

Identifiants

pubmed: 32318117
doi: 10.1186/s13099-020-00358-5
pii: 358
pmc: PMC7158114
doi:

Types de publication

Journal Article

Langues

eng

Pagination

20

Informations de copyright

© The Author(s) 2020.

Déclaration de conflit d'intérêts

Competing interestsThe authors declare that they have no competing interests.

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Auteurs

Mohammad M Rahman (MM)

1Department of Microbiology, Monash University, Clayton, VIC 3800 Australia.
2Infection and Immunity Program, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800 Australia.

Alexandra Tikhomirova (A)

1Department of Microbiology, Monash University, Clayton, VIC 3800 Australia.
2Infection and Immunity Program, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800 Australia.

Joyanta K Modak (JK)

1Department of Microbiology, Monash University, Clayton, VIC 3800 Australia.
2Infection and Immunity Program, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800 Australia.

Melanie L Hutton (ML)

1Department of Microbiology, Monash University, Clayton, VIC 3800 Australia.
2Infection and Immunity Program, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800 Australia.

Claudiu T Supuran (CT)

3Neurofarba Department, Sezione di Scienze Farmaceutiche, Universita degli Studi di Firenze, Via U. Schiff 6, Sesto Fiorentino, 50019 Florence, Italy.

Anna Roujeinikova (A)

1Department of Microbiology, Monash University, Clayton, VIC 3800 Australia.
2Infection and Immunity Program, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800 Australia.
4Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC Australia.

Classifications MeSH