Two-Dimensional Transition Metal Dichalcogenides: Synthesis, Biomedical Applications and Biosafety Evaluation.

2D TMDCs biomedical application biosafety evaluation modification methods synthesis

Journal

Frontiers in bioengineering and biotechnology
ISSN: 2296-4185
Titre abrégé: Front Bioeng Biotechnol
Pays: Switzerland
ID NLM: 101632513

Informations de publication

Date de publication:
2020
Historique:
received: 29 01 2020
accepted: 06 03 2020
entrez: 23 4 2020
pubmed: 23 4 2020
medline: 23 4 2020
Statut: epublish

Résumé

Recently, two-dimensional transition metal dichalcogenides (2D TMDCs) have drawn certain attentions in many fields. The unique and diversified electronic structure and ultrathin sheet structure of 2D TMDCs offer opportunities for moving ahead of other 2D nanomaterials such as graphene and expanding the wide application of inorganic 2D nanomaterials in many fields. For a better understanding of 2D TMDCs, one needs to know methods for their synthesis and modification, as well as their potential applications and possible biological toxicity. Herein, we summarized the recent research progress of 2D TMDCs with particular focus on their biomedical applications and potential health risks. Firstly, two kinds of synthesis methods of 2D TMDCs, top-down and bottom-up, and methods for their surface functionalization are reviewed. Secondly, the applications of 2D TMDCs in the field of biomedicine, including drug loading, photothermal therapy, biological imaging and biosensor were summarized. After that, we presented the existing researches on biosafety evaluation of 2D TMDCs. At last, we discussed major research gap in current researches and challenges and coping strategies in future studies.

Identifiants

pubmed: 32318550
doi: 10.3389/fbioe.2020.00236
pmc: PMC7154136
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

236

Informations de copyright

Copyright © 2020 Zhou, Sun and Bai.

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Auteurs

Xiaofei Zhou (X)

Faculty of Science and Technology, Bohai Campus, Hebei Agricultural University, Cangzhou, China.

Hainan Sun (H)

Shandong Vocational College of Light Industry, Zibo, China.

Xue Bai (X)

School of Public Health, Shandong University, Jinan, China.

Classifications MeSH