Computational model for detector timing effects in Compton-camera based prompt-gamma imaging for proton radiotherapy.
Journal
Physics in medicine and biology
ISSN: 1361-6560
Titre abrégé: Phys Med Biol
Pays: England
ID NLM: 0401220
Informations de publication
Date de publication:
18 06 2020
18 06 2020
Historique:
pubmed:
23
4
2020
medline:
21
10
2020
entrez:
23
4
2020
Statut:
epublish
Résumé
This paper describes a realistic simulation of a Compton-camera (CC) based prompt-gamma (PG) imaging system for proton range verification for a range of clinical dose rates, and its comparison to PG measured data with a pre-clinical CC. We used a Monte Carlo plus Detector Effects (MCDE) model to simulate the production of prompt gamma-rays (PG) and their energy depositions in the CC. With Monte Carlo, we simulated PG emission resulting from irradiation of a high density polyethylene phantom with a 150 MeV proton pencil beam at dose rates of 5.0 × 10
Identifiants
pubmed: 32320971
doi: 10.1088/1361-6560/ab8bf0
pmc: PMC8808425
mid: NIHMS1771732
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
125004Subventions
Organisme : NCI NIH HHS
ID : R01 CA187416
Pays : United States
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