Prevalence and heritability of handedness in a Hong Kong Chinese twin and singleton sample.
Chinese children
Edinburgh handedness inventory
Handedness
Pegboard
Twins
Journal
BMC psychology
ISSN: 2050-7283
Titre abrégé: BMC Psychol
Pays: England
ID NLM: 101627676
Informations de publication
Date de publication:
22 Apr 2020
22 Apr 2020
Historique:
received:
23
11
2019
accepted:
31
03
2020
entrez:
24
4
2020
pubmed:
24
4
2020
medline:
15
8
2020
Statut:
epublish
Résumé
Left-handedness prevalence has been consistently reported at around 10% with heritability estimates at around 25%. Higher left-handedness prevalence has been reported in males and in twins. Lower prevalence has been reported in Asia, but it remains unclear whether this is due to biological or cultural factors. Most studies are based on samples with European ethnicities and using the preferred hand for writing as key assessment. Here, we investigated handedness in a sample of Chinese school children in Hong Kong, including 426 singletons and 205 pairs of twins, using both the Edinburgh Handedness Inventory and Pegboard Task. Based on a binary definition of writing hand, we found a higher prevalence of left-handedness (8%) than what was previously reported in Asian datasets. We found no evidence of increased left-handedness in twins, but our results were in line with previous findings showing that males have a higher tendency to be left-handed than females. Heritability was similar for both hand preference (21%) and laterality indexes (22%). However, these two handedness measures present only a moderate correlation (.42) and appear to be underpinned by different genetic factors. In summary, we report new reference data for an ethnic group usually underrepresented in the literature. Our heritability analysis supports the idea that different measures will capture different components of handedness and, as a consequence, datasets assessed with heterogeneous criteria are not easily combined or compared.
Sections du résumé
BACKGROUND
BACKGROUND
Left-handedness prevalence has been consistently reported at around 10% with heritability estimates at around 25%. Higher left-handedness prevalence has been reported in males and in twins. Lower prevalence has been reported in Asia, but it remains unclear whether this is due to biological or cultural factors. Most studies are based on samples with European ethnicities and using the preferred hand for writing as key assessment. Here, we investigated handedness in a sample of Chinese school children in Hong Kong, including 426 singletons and 205 pairs of twins, using both the Edinburgh Handedness Inventory and Pegboard Task.
RESULTS
RESULTS
Based on a binary definition of writing hand, we found a higher prevalence of left-handedness (8%) than what was previously reported in Asian datasets. We found no evidence of increased left-handedness in twins, but our results were in line with previous findings showing that males have a higher tendency to be left-handed than females. Heritability was similar for both hand preference (21%) and laterality indexes (22%). However, these two handedness measures present only a moderate correlation (.42) and appear to be underpinned by different genetic factors.
CONCLUSION
CONCLUSIONS
In summary, we report new reference data for an ethnic group usually underrepresented in the literature. Our heritability analysis supports the idea that different measures will capture different components of handedness and, as a consequence, datasets assessed with heterogeneous criteria are not easily combined or compared.
Identifiants
pubmed: 32321583
doi: 10.1186/s40359-020-00401-9
pii: 10.1186/s40359-020-00401-9
pmc: PMC7178737
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
37Subventions
Organisme : Research Grants Council (RGC) of HKSAR
ID : CUHK8/CRF/13G & C4054-17WF
Organisme : Chinese University of Hong Kong
ID : 4930703
Organisme : Hong Kong Grants Council
ID : Hong Kong: Scotland Collaborative Research Partnership
Organisme : Scottish Funding Council
ID : Hong Kong: Scotland Collaborative Research Partnership
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