Constitutive and Stress-Induced Psychomotor Cortical Responses to Compound K Supplementation.
EEG
cortical activity
event-related potentials
exercise
ginsenoside
psychomotor performance
source localization
stress
Journal
Frontiers in neuroscience
ISSN: 1662-4548
Titre abrégé: Front Neurosci
Pays: Switzerland
ID NLM: 101478481
Informations de publication
Date de publication:
2020
2020
Historique:
received:
05
11
2019
accepted:
17
03
2020
entrez:
24
4
2020
pubmed:
24
4
2020
medline:
24
4
2020
Statut:
epublish
Résumé
Isolated ginsenoside metabolites such as Compound K (CK) are of increasing interest to consumer and clinical populations as safe and non-pharmacological means to enhance psychomotor performance constitutively and in response to physical or cognitive stress. Nevertheless, the influence of CK on behavioral performance and EEG measures of cortical activity in humans is undetermined. In this double-blinded, placebo-controlled, counterbalanced within-group study, dose-dependent responses to CK (placebo, 160 and 960 mg) were assessed after 2 weeks of supplementation in nineteen healthy men and women (age: 39.9 ± 7.9 year, height 170.2 ± 8.6 cm, weight 79.7 ± 11.9 kg). Performance on upper- and lower-body choice reaction tests (CRTs) was tested before and after intense lower-body anaerobic exercise. Treatment- and stress-related changes in brain activity were measured with high-density EEG based on event-related potentials, oscillations, and source activity. Upper- (-12.3 ± 3.5 ms,
Identifiants
pubmed: 32322188
doi: 10.3389/fnins.2020.00315
pmc: PMC7158875
doi:
Types de publication
Journal Article
Langues
eng
Pagination
315Informations de copyright
Copyright © 2020 Flanagan, Proessl, Dunn-Lewis, Canino, Sterczala, Connaboy, DuPont, Caldwell and Kraemer.
Références
Prog Neurobiol. 2008 Nov;86(3):156-85
pubmed: 18824212
Arch Pharm Res. 2000 Apr;23(2):172-7
pubmed: 10836746
Biol Pharm Bull. 2015;38(9):1415-9
pubmed: 26328499
Brain Res. 2012 May 9;1453:87-101
pubmed: 22480735
Percept Mot Skills. 1998 Aug;87(1):175-85
pubmed: 9760644
Pharmacol Biochem Behav. 2016 Jan;140:17-26
pubmed: 26528894
Planta Med. 1997 Oct;63(5):436-40
pubmed: 9342949
Neuropsychologia. 2014 May;58:33-51
pubmed: 24709570
J Neurophysiol. 2019 Feb 1;121(2):471-479
pubmed: 30565971
Front Integr Neurosci. 2013 Dec 05;7:83
pubmed: 24367301
J Vet Sci. 2013;14(3):249-56
pubmed: 23820200
J Pharmacol Sci. 2019 Mar;139(3):223-230
pubmed: 30799178
J Neurochem. 2010 Aug;114(4):1085-96
pubmed: 20524959
Planta Med. 1996 Oct;62(5):453-7
pubmed: 8923812
Biochem Pharmacol. 2011 Aug 1;82(3):278-86
pubmed: 21600888
Biol Pharm Bull. 2005 Nov;28(11):2102-5
pubmed: 16272697
Prog Brain Res. 1993;98:345-55
pubmed: 8248523
Nutr Rev. 2014 May;72(5):319-33
pubmed: 24666107
Trends Neurosci. 2007 Jul;30(7):317-24
pubmed: 17499860
Br J Sports Med. 2015 Apr;49(8):556-60
pubmed: 23729175
Electromyogr Clin Neurophysiol. 1994 Jan-Feb;34(1):5-13
pubmed: 8168458
Neurosci Biobehav Rev. 2016 Dec;71:418-443
pubmed: 27693229
J Neurophysiol. 1993 Oct;70(4):1385-400
pubmed: 8283204
Int J Psychophysiol. 2016 May;103:43-52
pubmed: 25660301
Trends Neurosci. 1994 Feb;17(2):75-9
pubmed: 7512772
Trends Cogn Sci. 2012 Dec;16(12):606-17
pubmed: 23141428
PLoS One. 2014 Dec 11;9(12):e114649
pubmed: 25500579
J Ginseng Res. 2016 Oct;40(4):437-444
pubmed: 27746698
Indian J Psychol Med. 2010 Jul;32(2):131-5
pubmed: 21716775
Psychol Bull. 2005 Jul;131(4):510-32
pubmed: 16060800
Biomed Eng Lett. 2017 Feb 6;7(3):193-203
pubmed: 30603166
Clin Neurophysiol. 2007 Oct;118(10):2128-48
pubmed: 17573239
Neuroreport. 1999 Mar 17;10(4):675-9
pubmed: 10208529
Front Pharmacol. 2018 May 01;9:423
pubmed: 29765322
Psychophysiology. 2017 Jan;54(1):146-157
pubmed: 28000253
Prog Neuropsychopharmacol Biol Psychiatry. 2009 Nov 13;33(8):1417-24
pubmed: 19632285
Chem Pharm Bull (Tokyo). 2007 Oct;55(10):1522-7
pubmed: 17917300
Neuroimage. 2002 Sep;17(1):161-73
pubmed: 12482074
Clin Neurophysiol. 2001 Aug;112(8):1400-7
pubmed: 11459679
J Ethnopharmacol. 2009 Feb 25;122(1):143-8
pubmed: 19146939
J Int Soc Sports Nutr. 2012 May 18;9(1):23
pubmed: 22607394
Sports Med. 2002;32(9):555-66
pubmed: 12096929
IEEE Trans Biomed Eng. 1998 Aug;45(8):980-97
pubmed: 9691573
Oncotarget. 2018 Sep 11;9(71):33601-33620
pubmed: 30323902
J Pharm Pharmacol. 2010 Feb;62(2):263-71
pubmed: 20487207
Biol Pharm Bull. 2015;38(2):331-5
pubmed: 25747994
Brain Topogr. 2003 Spring;15(3):141-52
pubmed: 12705810
J Med Food. 2018 Jan;21(1):104-112
pubmed: 28981384
Brain Res Rev. 2007 Jan;53(1):63-88
pubmed: 16887192
Phytother Res. 2010 Dec;24(12):1748-54
pubmed: 20564503
J Clin Neurophysiol. 1994 Jan;11(1):111-3
pubmed: 8195414
J Pharmacol Exp Ther. 2012 Apr;341(1):59-67
pubmed: 22207656
J Agric Food Chem. 2016 Apr 13;64(14):2855-64
pubmed: 27012214
Neuroimage Clin. 2013 Jul 17;3:39-46
pubmed: 24179847
Food Funct. 2016 Nov 9;7(11):4506-4515
pubmed: 27801453
Front Neurosci. 2019 May 03;13:444
pubmed: 31130842
Epilepsy Res. 2006 Aug;70(2-3):244-56
pubmed: 16782310
Methods Find Exp Clin Pharmacol. 2002;24 Suppl D:5-12
pubmed: 12575463
Clin Neurophysiol. 2005 Nov;116(11):2693-700
pubmed: 16221568
Clin Neurophysiol. 2002 May;113(5):702-12
pubmed: 11976050
Biol Pharm Bull. 2000 Dec;23(12):1481-5
pubmed: 11145182
Epilepsia. 2005 Jan;46(1):15-22
pubmed: 15660764
IEEE Trans Neural Netw. 1999;10(3):626-34
pubmed: 18252563
Clin Neurophysiol. 2007 Dec;118(12):2692-9
pubmed: 17905651
Brain Res Cogn Brain Res. 2001 Apr;11(2):281-7
pubmed: 11275489
Brain Topogr. 1992 Winter;5(2):189-94
pubmed: 1489649