Cerebral metastasis from osteosarcoma: "Bone" in the brain.
Brain metastasis
Calcification
Osteosarcoma
Journal
Radiology case reports
ISSN: 1930-0433
Titre abrégé: Radiol Case Rep
Pays: Netherlands
ID NLM: 101467888
Informations de publication
Date de publication:
Jun 2020
Jun 2020
Historique:
received:
28
02
2020
accepted:
16
03
2020
entrez:
24
4
2020
pubmed:
24
4
2020
medline:
24
4
2020
Statut:
epublish
Résumé
Although brain metastases from bone and soft tissue sarcoma are uncommon, advances in sarcoma treatment have led to an increasing incidence of them. We present a 23-year-old male with a history of metastatic femoral osteosarcoma, who presented with headache and unsteady gait and was diagnosed with a cerebellar metastasis. CT scan revealed a mass in the left cerebellar parenchyma with large intralesional central calcification and perilesional edema. Corticosteroid treatment led to neurological symptoms resolution, with a rapid tapering. The patient had also lung metastases and we opted to administer systemic treatment with the tyrosine kinase inhibitor cabozantinib. Given the relative radioresistance of osteosarcomas, the patient did not receive radiation therapy.
Identifiants
pubmed: 32322331
doi: 10.1016/j.radcr.2020.03.020
pii: S1930-0433(20)30100-X
pmc: PMC7171257
doi:
Types de publication
Case Reports
Langues
eng
Pagination
780-783Informations de copyright
© 2020 The Authors. Published by Elsevier Inc. on behalf of University of Washington.
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