Exploring the presence of dental anomalies as a consequence of treatment of malignancy: A case report.
Anomalies
Drugs
Hodgkins lymphoma
Tooth agenesis
Tuberculous
Journal
Journal of oral biology and craniofacial research
ISSN: 2212-4268
Titre abrégé: J Oral Biol Craniofac Res
Pays: Netherlands
ID NLM: 101619156
Informations de publication
Date de publication:
Historique:
received:
07
03
2020
revised:
31
03
2020
accepted:
04
04
2020
entrez:
24
4
2020
pubmed:
24
4
2020
medline:
24
4
2020
Statut:
ppublish
Résumé
Simultaneous presentation of tuberculosis (TB) and lymphoma in a young child is indeed a very rare entity. Malignancy such as Hodgkin's disease (HD) most commonly causes suppression of the cell-mediated immunity, which makes the individual, especially children, more prone to tuberculous infection. One of the non-life threatening complications in these young cancer survivors is the associated dental anomalies. These can seriously impair the quality of life of teenagers and young adults. Higher incidence of caries, discoloration of teeth or even early loss of teeth requiring dental prosthesis, can be associated with the use of cytostatic drugs. These drugs can also disturb odontogenesis, resulting in the absence of tooth buds, microdontia, dilacerations or shortening of tooth roots. Some of the anticancer drugs, including busulfan, cyclophosphamide, doxorubicin etc. May particularly play a significant role in the development of dental anomalies. This paper is a short review and case report of an 11 year old child having oligodontia and secondary dental complications caused as a side effect of treatment of Hodgkin's lymphoma with Tuberculous Lymphadenitis.
Identifiants
pubmed: 32322476
doi: 10.1016/j.jobcr.2020.04.002
pii: S2212-4268(20)30035-X
pmc: PMC7163057
doi:
Types de publication
Journal Article
Langues
eng
Pagination
135-137Informations de copyright
© 2020 Craniofacial Research Foundation. Published by Elsevier B.V. All rights reserved.
Références
Acta Odontol Scand. 1996 Oct;54(5):287-94
pubmed: 8923922
Pediatrics. 1984 Jun;73(6):816-23
pubmed: 6728583
Turk J Haematol. 2018 Oct 16;36(3):155-161
pubmed: 30322830
Cancer Res Treat. 2016 Apr;48(2):658-67
pubmed: 26511809
Clin Genet. 2017 Nov;92(5):467-476
pubmed: 28155232
J Clin Pediatr Dent. 2005 Winter;29(2):167-74
pubmed: 15719924
Am J Med Genet A. 2011 Jul;155A(7):1616-22
pubmed: 21626677
BMJ Case Rep. 2016 Jan 06;2016:
pubmed: 26740271
Acta Odontol Scand. 1997 Jun;55(3):186-91
pubmed: 9226430