Determinants of Metabolic Health Across Body Mass Index Categories in Central Europe: A Comparison Between Swiss and Czech Populations.


Journal

Frontiers in public health
ISSN: 2296-2565
Titre abrégé: Front Public Health
Pays: Switzerland
ID NLM: 101616579

Informations de publication

Date de publication:
2020
Historique:
received: 10 12 2019
accepted: 18 03 2020
entrez: 24 4 2020
pubmed: 24 4 2020
medline: 24 4 2020
Statut: epublish

Résumé

Comparisons among countries can help to identify opportunities for the reduction of inequalities in cardiometabolic health. The present cross-sectional analysis and meta-analysis aim to address to what extent obesity traits, socioeconomic, and behavioral factors determine poor metabolic health across body mass index (BMI) categories in two urban population-based samples from Central Europe. Data from the CoLaus (~6,000 participants; Lausanne, Switzerland) and the Kardiovize Brno 2030 (~2,000 participants; Brno, Czech Republic) cohorts. For each cohort, logistic regression analyses were performed to identify the main determinants of poor metabolic health overall and stratified by body mass index (BMI) categories. The results of each cohort were then combined in a meta-analysis. We first observed that waist circumference and body fat mass were associated with metabolic health, especially in non-obese individuals. Moreover, increasing age, being male, having low-medium educational level, abdominal obesity, and high body fat mass were the main determinants of the metabolically unhealthy profile in both cohorts. Meta-analysis stratified by BMI categories confirmed the previous results with slight differences across BMI categories. In fact, increasing age and being male were the main determinants of poor metabolic health independent of obesity status. In contrast, low educational level and current smoking were associated with poor metabolic health only in non-obese individuals. In line, public health strategies against obesity and related comorbidities should aim to improve social conditions and to promote healthy lifestyles before the progression of metabolic disorders.

Identifiants

pubmed: 32322570
doi: 10.3389/fpubh.2020.00108
pmc: PMC7156604
doi:

Types de publication

Journal Article Meta-Analysis Research Support, Non-U.S. Gov't

Langues

eng

Pagination

108

Informations de copyright

Copyright © 2020 Kunzova, Maugeri, Medina-Inojosa, Lopez-Jimenez, Vinciguerra and Marques-Vidal.

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Auteurs

Sarka Kunzova (S)

International Clinical Research Center, St Anne's University Hospital, Brno, Czechia.

Andrea Maugeri (A)

International Clinical Research Center, St Anne's University Hospital, Brno, Czechia.
Department of Medical and Surgical Sciences and Advanced Technologies "GF Ingrassia", University of Catania, Catania, Italy.

Jose Medina-Inojosa (J)

Division of Preventive Cardiology, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, United States.

Francisco Lopez-Jimenez (F)

Division of Preventive Cardiology, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, United States.

Manlio Vinciguerra (M)

International Clinical Research Center, St Anne's University Hospital, Brno, Czechia.

Pedro Marques-Vidal (P)

Department of Medicine, Internal Medicine, Lausanne University Hospital, Lausanne, Switzerland.

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Classifications MeSH