Genetic Engineering of Filamentous Fungi for Efficient Protein Expression and Secretion.
expression
filamentous fungi
genetic engineering
genome engineering
protein secretion
Journal
Frontiers in bioengineering and biotechnology
ISSN: 2296-4185
Titre abrégé: Front Bioeng Biotechnol
Pays: Switzerland
ID NLM: 101632513
Informations de publication
Date de publication:
2020
2020
Historique:
received:
15
01
2020
accepted:
19
03
2020
entrez:
24
4
2020
pubmed:
24
4
2020
medline:
24
4
2020
Statut:
epublish
Résumé
Filamentous fungi are considered as unique cell factories for protein production due to the high efficiency of protein secretion and superior capability of post-translational modifications. In this review, we firstly introduce the secretory pathway in filamentous fungi. We next summarize the current state-of-the-art works regarding how various genetic engineering strategies are applied for enhancing protein expression and secretion in filamentous fungi. Finally, in a future perspective, we discuss the great potential of genome engineering for further improving protein expression and secretion in filamentous fungi.
Identifiants
pubmed: 32322579
doi: 10.3389/fbioe.2020.00293
pmc: PMC7156587
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
293Informations de copyright
Copyright © 2020 Wang, Zhong and Xiao.
Références
Sci Rep. 2018 Jul 30;8(1):11433
pubmed: 30061727
Microb Cell Fact. 2007 Oct 29;6:34
pubmed: 17967194
Enzyme Microb Technol. 2017 Nov;106:83-87
pubmed: 28859814
Appl Microbiol Biotechnol. 2011 Dec;92(6):1197-206
pubmed: 21822643
Annu Rev Biochem. 2010;79:777-802
pubmed: 20533886
J Biol Chem. 2002 Dec 6;277(49):47692-700
pubmed: 12359722
Plasmid. 2014 Jan;71:16-22
pubmed: 24418391
Curr Opin Cell Biol. 2011 Apr;23(2):176-83
pubmed: 21075612
J Biol Chem. 2013 Jul 19;288(29):21043-54
pubmed: 23760507
Acta Chim Slov. 2014;61(4):709-17
pubmed: 25551710
Cell Mol Life Sci. 2008 Sep;65(18):2781-9
pubmed: 18726180
J Cell Biol. 2002 May 13;157(4):631-43
pubmed: 12011112
Virulence. 2011 Jan-Feb;2(1):12-21
pubmed: 21217201
Biosci Biotechnol Biochem. 2003 Feb;67(2):455-9
pubmed: 12729022
Mol Microbiol. 2011 Mar;79(5):1151-67
pubmed: 21205013
Biotechnol Genet Eng Rev. 1991;9:327-67
pubmed: 1839127
Appl Environ Microbiol. 2010 Sep;76(17):5718-27
pubmed: 20622126
Biotechnol Biofuels. 2014 May 23;7:78
pubmed: 24904688
World J Microbiol Biotechnol. 2014 Oct;30(10):2587-95
pubmed: 24898179
Biotechnol Adv. 2012 Sep-Oct;30(5):1119-39
pubmed: 21968147
Mycol Res. 2006 Jan;110(Pt 1):4-13
pubmed: 16378719
Genetics. 1996 Feb;142(2):393-406
pubmed: 8852839
Nat Commun. 2017 May 04;8:15187
pubmed: 28469255
Biotechnol Biofuels. 2017 Jan 3;10:1
pubmed: 28053662
Fungal Genet Biol. 2009 Mar;46 Suppl 1:S141-52
pubmed: 18824119
Microb Cell Fact. 2018 Jun 16;17(1):95
pubmed: 29908567
BMC Genomics. 2012 Jul 30;13:350
pubmed: 22846479
Genetics. 1999 Mar;151(3):1015-25
pubmed: 10049919
Appl Environ Microbiol. 2003 Dec;69(12):6979-86
pubmed: 14660339
Biotechnol Lett. 2018 Jun;40(6):949-955
pubmed: 29605944
Metab Eng. 2017 May;41:1-10
pubmed: 28216108
Glycobiology. 2008 Aug;18(8):626-37
pubmed: 18504293
Trends Biotechnol. 2005 Sep;23(9):468-74
pubmed: 15967521
PLoS Pathog. 2008 Nov;4(11):e1000200
pubmed: 18989462
PLoS One. 2013 Apr 29;8(4):e62512
pubmed: 23658635
Appl Environ Microbiol. 2002 Feb;68(2):846-51
pubmed: 11823227
Trends Biotechnol. 2002 May;20(5):200-6
pubmed: 11943375
Biotechnol Adv. 2015 Nov 15;33(7):1420-32
pubmed: 25450192
Physiol Rev. 2011 Jan;91(1):119-49
pubmed: 21248164
Fungal Biol Biotechnol. 2019 Oct 18;6:16
pubmed: 31641527
Microbiology. 2012 Jan;158(Pt 1):46-57
pubmed: 22053009
Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):4429-4434
pubmed: 29643074
J Biol Chem. 2011 Apr 1;286(13):11479-91
pubmed: 21228276
Fungal Genet Biol. 2014 Dec;73:69-82
pubmed: 25312861
J Biol Chem. 2007 Aug 3;282(31):22775-85
pubmed: 17553800
Fungal Genet Biol. 2008 Jan;45(1):17-27
pubmed: 17977034
Appl Microbiol Biotechnol. 2018 Nov;102(21):9291-9301
pubmed: 30155751
Appl Environ Microbiol. 2004 Sep;70(9):5145-52
pubmed: 15345393
Nature. 2006 Nov 23;444(7118):507-11
pubmed: 17086193
Cell. 2017 Nov 30;171(6):1453-1467.e13
pubmed: 29153834
J Ind Microbiol Biotechnol. 2019 Nov;46(11):1603-1610
pubmed: 31375945
Adv Appl Microbiol. 2012;81:1-61
pubmed: 22958526
Trends Biochem Sci. 2006 Mar;31(3):156-63
pubmed: 16473013
Fungal Genet Biol. 2001 Aug;33(3):155-71
pubmed: 11495573
J Biol Chem. 2003 Nov 7;278(45):45011-20
pubmed: 12941955
Nature. 1993 Mar 25;362(6418):318-24
pubmed: 8455717
mBio. 2017 Apr 18;8(2):
pubmed: 28420736
Sci Rep. 2016 Jun 07;6:27223
pubmed: 27270141
Nat Biotechnol. 2017 Jan;35(1):48-55
pubmed: 27941803
Appl Microbiol Biotechnol. 2011 Jan;89(2):357-73
pubmed: 20922374
Appl Microbiol Biotechnol. 2020 Feb;104(4):1661-1671
pubmed: 31865439
Cell Rep. 2018 May 1;23(5):1373-1386
pubmed: 29719251
Appl Environ Microbiol. 2015 Jan;81(2):533-43
pubmed: 25362068
Microb Cell Fact. 2018 Jun 16;17(1):96
pubmed: 29908565
Appl Microbiol Biotechnol. 2003 Feb;60(6):726-32
pubmed: 12664153
Biotechnol Biofuels. 2015 Aug 19;8:121
pubmed: 26288653
Biotechnol Biofuels. 2018 Sep 24;11:261
pubmed: 30258495
Appl Biochem Biotechnol. 2011 Nov;165(5-6):1169-77
pubmed: 21845444
Nat Biotechnol. 2018 Jul;36(6):505-508
pubmed: 29734295