Reinventing Extremity Amputation in the Era of Functional Limb Restoration.


Journal

Annals of surgery
ISSN: 1528-1140
Titre abrégé: Ann Surg
Pays: United States
ID NLM: 0372354

Informations de publication

Date de publication:
01 02 2021
Historique:
pubmed: 24 4 2020
medline: 20 2 2021
entrez: 24 4 2020
Statut: ppublish

Résumé

Recent progress in biomechatronics and vascularized composite allotransplantation have occurred in the absence of congruent advancements in the surgical approaches generally utilized for limb amputation. Consideration of these advances, as well as of both novel and time-honored reconstructive surgical techniques, argues for a fundamental reframing of the way in which amputation procedures should be performed. We review sentinel developments in external prosthetic limb technology and limb transplantation, in addition to standard and emerging reconstructive surgical techniques relevant to limb modification, and then propose a new paradigm for limb amputation. An approach to limb amputation based on the availability of native tissues is proposed, with the intent of maximizing limb function, limiting neuropathic pain, restoring limb perception/proprioception and mitigating limb atrophy. We propose a reinvention of the manner in which limb amputations are performed, framed in the context of time-tested reconstructive techniques, as well as novel, state-of-the-art surgical procedures. Implementation of the proposed techniques in the acute setting has the potential to elevate advanced limb replacement strategies to a clinical solution that perhaps exceeds what is possible through traditional surgical approaches to limb salvage. We therefore argue that amputation, performed with the intent of optimizing the residuum for interaction with either a bionic or a transplanted limb, should be viewed not as a surgical failure, but as an alternative form of limb reconstruction.

Sections du résumé

BACKGROUND
Recent progress in biomechatronics and vascularized composite allotransplantation have occurred in the absence of congruent advancements in the surgical approaches generally utilized for limb amputation. Consideration of these advances, as well as of both novel and time-honored reconstructive surgical techniques, argues for a fundamental reframing of the way in which amputation procedures should be performed.
METHODS
We review sentinel developments in external prosthetic limb technology and limb transplantation, in addition to standard and emerging reconstructive surgical techniques relevant to limb modification, and then propose a new paradigm for limb amputation.
RESULTS
An approach to limb amputation based on the availability of native tissues is proposed, with the intent of maximizing limb function, limiting neuropathic pain, restoring limb perception/proprioception and mitigating limb atrophy.
CONCLUSIONS
We propose a reinvention of the manner in which limb amputations are performed, framed in the context of time-tested reconstructive techniques, as well as novel, state-of-the-art surgical procedures. Implementation of the proposed techniques in the acute setting has the potential to elevate advanced limb replacement strategies to a clinical solution that perhaps exceeds what is possible through traditional surgical approaches to limb salvage. We therefore argue that amputation, performed with the intent of optimizing the residuum for interaction with either a bionic or a transplanted limb, should be viewed not as a surgical failure, but as an alternative form of limb reconstruction.

Identifiants

pubmed: 32324689
pii: 00000658-202102000-00013
doi: 10.1097/SLA.0000000000003895
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

269-279

Informations de copyright

Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.

Déclaration de conflit d'intérêts

The authors report no conflicts of interest.

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Auteurs

Hugh M Herr (HM)

Massachusetts Institute of Technology, Center for Extreme Bionics, Cambridge, MA.

Tyler R Clites (TR)

Massachusetts Institute of Technology, Center for Extreme Bionics, Cambridge, MA.

Shriya Srinivasan (S)

Massachusetts Institute of Technology, Center for Extreme Bionics, Cambridge, MA.

Simon G Talbot (SG)

Division of Plastic Surgery, Brigham and Women's Hospital, Boston, MA.

Gregory A Dumanian (GA)

Division of Plastic Surgery, Northwestern Memorial Hospital, Chicago, IL.

Paul S Cederna (PS)

Section of Plastic Surgery, University of Michigan, Ann Arbor, MI.

Matthew J Carty (MJ)

Massachusetts Institute of Technology, Center for Extreme Bionics, Cambridge, MA.
Division of Plastic Surgery, Brigham and Women's Hospital, Boston, MA.

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