A Randomized Controlled Open Label Crossover Trial to Study Vaginal Colonization of Orally Administered Lactobacillus Reuteri RC-14 and Rhamnosus GR-1 in Pregnant Women at High Risk for Preterm Labor.
Administration, Oral
Adolescent
Adult
Cross-Over Studies
Female
Humans
Limosilactobacillus reuteri
/ isolation & purification
Lacticaseibacillus rhamnosus
/ isolation & purification
Obstetric Labor, Premature
/ etiology
Pregnancy
Pregnant Women
Premature Birth
/ etiology
Probiotics
/ administration & dosage
Risk
Vigna
/ microbiology
Young Adult
abnormal vaginal flora
bacterial vaginosis
lactobacilli
pregnancy
preterm delivery
probiotics
Journal
Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595
Informations de publication
Date de publication:
19 Apr 2020
19 Apr 2020
Historique:
received:
05
03
2020
revised:
15
04
2020
accepted:
16
04
2020
entrez:
25
4
2020
pubmed:
25
4
2020
medline:
26
2
2021
Statut:
epublish
Résumé
Lactobacilli administration has been suggested for the treatment and prevention of bacterial vaginosis, which increases the risk for preterm birth. We aimed to evaluate the vaginal colonization of lactobacilli orally administered to pregnant women at risk for preterm birth. We performed a randomized and controlled crossover study between January 2016 and May 2017. Forty pregnant women at high risk for preterm birth with normal vaginal flora (Nugent score ≤ 3) were randomized to either receive two oral capsules/day each containing 5 × 10
Identifiants
pubmed: 32325794
pii: nu12041141
doi: 10.3390/nu12041141
pmc: PMC7230520
pii:
doi:
Types de publication
Journal Article
Randomized Controlled Trial
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Technion-Israel Institute of Technology
ID : N/A
Organisme : Altman Company, Israel
ID : N/A
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