New Insights into the Molecular Bases of Familial Alzheimer's Disease.
APOE alleles
APP mutations
Alzheimer’s disease
PSEN1
PSEN2
early onset AD
familial AD
genetics of AD
germline mutations
late onset AD
Journal
Journal of personalized medicine
ISSN: 2075-4426
Titre abrégé: J Pers Med
Pays: Switzerland
ID NLM: 101602269
Informations de publication
Date de publication:
19 Apr 2020
19 Apr 2020
Historique:
received:
25
03
2020
revised:
14
04
2020
accepted:
17
04
2020
entrez:
25
4
2020
pubmed:
25
4
2020
medline:
25
4
2020
Statut:
epublish
Résumé
Like several neurodegenerative disorders, such as Prion and Parkinson diseases, Alzheimer's disease (AD) is characterized by spreading mechanism of aggregated proteins in the brain in a typical "prion-like" manner. Recent genetic studies have identified in four genes associated with inherited AD (amyloid precursor protein-
Identifiants
pubmed: 32325882
pii: jpm10020026
doi: 10.3390/jpm10020026
pmc: PMC7354425
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
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