Socioeconomic disparities in SUDEP in the US.
Journal
Neurology
ISSN: 1526-632X
Titre abrégé: Neurology
Pays: United States
ID NLM: 0401060
Informations de publication
Date de publication:
16 06 2020
16 06 2020
Historique:
received:
09
04
2019
accepted:
05
12
2019
pubmed:
25
4
2020
medline:
22
9
2020
entrez:
25
4
2020
Statut:
ppublish
Résumé
To determine the impact of socioeconomic status (SES) on sudden unexpected death in epilepsy (SUDEP) rates. We queried all decedents presented for medico-legal investigation at 3 medical examiner (ME) offices across the country (New York City, Maryland, San Diego County) in 2009 to 2010 and 2014 to 2015. We identified all decedents for whom epilepsy/seizure was listed as cause/contributor to death or comorbid condition on the death certificate. We then reviewed all available reports. Decedents determined to have SUDEP were included for analysis. We used median income in the ZIP code of residence as a surrogate for SES. For each region, zip code regions were ranked by median household income and divided into quartiles based on total population for 2 time periods. Region-, age-, and income-adjusted epilepsy prevalence was estimated in each zip code. SUDEP rates in the highest and lowest SES quartiles were evaluated to determine disparity. Examined SUDEP rates in 2 time periods were also compared. There were 159 and 43 SUDEP cases in the lowest and highest SES quartiles. ME-investigated SUDEP rate ratio between the lowest and highest SES quartiles was 2.6 (95% confidence interval [CI] 1.7-4.1, ME-investigated SUDEP incidence was significantly higher in people with the lowest SES compared to the highest SES. The difference persisted over a 5-year period despite decreased overall SUDEP rates.
Identifiants
pubmed: 32327496
pii: WNL.0000000000009463
doi: 10.1212/WNL.0000000000009463
pmc: PMC7455330
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e2555-e2566Subventions
Organisme : NCATS NIH HHS
ID : UL1 TR001445
Pays : United States
Commentaires et corrections
Type : CommentIn
Informations de copyright
© 2020 American Academy of Neurology.
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