The 4 D's of Pellagra and Progress.

CO2 emissions COVID-19 Climate change NAD worlds Parkinson disease anthropocene coronavirus deaths of despair demographic transition disease X disease transitions meat metabolic rift new levellers nicotinamide protonopathy

Journal

International journal of tryptophan research : IJTR
ISSN: 1178-6469
Titre abrégé: Int J Tryptophan Res
Pays: United States
ID NLM: 101513378

Informations de publication

Date de publication:
2020
Historique:
received: 12 12 2019
accepted: 06 02 2020
entrez: 25 4 2020
pubmed: 25 4 2020
medline: 25 4 2020
Statut: epublish

Résumé

Nicotinamide homeostasis is a candidate common denominator to explain smooth transitions, whether demographic, epidemiological or economic. This 'NAD world', dependent on hydrogen-based energy, is not widely recognised as it is neither measured nor viewed from a sufficiently multi-genomic or historical perspective. Reviewing the importance of meat and nicotinamide balances during our co-evolution, recent history suggests that populations only modernise and age well with low fertility on a suitably balanced diet. Imbalances on the low meat side lead to an excess of infectious disease, short lives and boom-bust demographics. On the high side, meat has led to an excess of degenerative, allergic and metabolic disease and low fertility. A 'Goldilocks' diet derived from mixed and sustainable farming (preserving the topsoil) allows for high intellectual capital, height and good health with controlled population growth resulting in economic growth and prosperity. Implementing meat equity worldwide could lead to progress for future generations on 'spaceship' earth by establishing control over population quality, thermostat and biodiversity, if it is not already too late.

Identifiants

pubmed: 32327922
doi: 10.1177/1178646920910159
pii: 10.1177_1178646920910159
pmc: PMC7163231
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

1178646920910159

Informations de copyright

© The Author(s) 2020.

Déclaration de conflit d'intérêts

Declaration of conflicting interests:The author(s) declared no potential conflicts of interest with respect to the research, authorship and/or publication of this article.

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Auteurs

Adrian C Williams (AC)

Department of Neurology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.

Lisa J Hill (LJ)

School of Biomedical Sciences, Institute of Clinical Sciences, University of Birmingham, Birmingham, UK.

Classifications MeSH