Zika among international travellers presenting to GeoSentinel sites, 2012-2019: implications for clinical practice.
Guillain-Barre syndrome
Survey
Zika diagnostics
declining epidemic
sentinel surveillance
Journal
Journal of travel medicine
ISSN: 1708-8305
Titre abrégé: J Travel Med
Pays: England
ID NLM: 9434456
Informations de publication
Date de publication:
14 Jul 2020
14 Jul 2020
Historique:
received:
18
02
2020
revised:
15
04
2020
accepted:
17
04
2020
pubmed:
25
4
2020
medline:
17
6
2021
entrez:
25
4
2020
Statut:
ppublish
Résumé
International travellers contribute to the rapid spread of Zika virus (ZIKV) and its sentinel identification globally. We describe ZIKV infections among international travellers seen at GeoSentinel sites with a focus on ZIKV acquired in the Americas and the Caribbean, describe countries of exposure and traveller characteristics, and assess ZIKV diagnostic testing by site. Records with an international travel-related diagnosis of confirmed or probable ZIKV from January 2012 through December 2019 reported to GeoSentinel with a recorded illness onset date were included to show reported cases over time. Records from March 2016 through December 2019 with an exposure region of the Americas or the Caribbean were included in the descriptive analysis. A survey was conducted to assess the availability, accessibility and utilization of ZIKV diagnostic tests at GeoSentinel sites. GeoSentinel sites reported 525 ZIKV cases from 2012 through 2019. Between 2012 and 2014, eight cases were reported, and all were acquired in Asia or Oceania. After 2014, most cases were acquired in the Americas or the Caribbean, a large decline in ZIKV cases occurred in 2018-19.Between March 2016 and December 2019, 423 patients acquired ZIKV in the Americas or the Caribbean, peak reporting to these regions occurred in 2016 [330 cases (78%)]. The median age was 36 years (range: 3-92); 63% were female. The most frequent region of exposure was the Caribbean (60%). Thirteen travellers were pregnant during or after travel; one had a sexually acquired ZIKV infection. There was one case of fetal anomaly and two travellers with Guillain-Barré syndrome. GeoSentinel sites reported various challenges to diagnose ZIKV effectively. ZIKV should remain a consideration for travellers returning from areas with risk of ZIKV transmission. Travellers should discuss their travel plans with their healthcare providers to ensure ZIKV prevention measures are taken.
Identifiants
pubmed: 32330261
pii: 5824831
doi: 10.1093/jtm/taaa061
pmc: PMC7604850
mid: NIHMS1589820
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Intramural CDC HHS
ID : CC999999
Pays : United States
Organisme : NCEZID CDC HHS
ID : U50 CK000189
Pays : United States
Informations de copyright
Published by Oxford University Press 2020.
Références
N Engl J Med. 2009 Jun 11;360(24):2536-43
pubmed: 19516034
J Travel Med. 2018 Jul 1;25(1):
pubmed: 30016469
J Travel Med. 2018 Jan 1;25(1):
pubmed: 30289482
J Infect Dis. 2018 Mar 13;217(7):1060-1068
pubmed: 29294035
Am J Trop Med Hyg. 2013 Sep;89(3):516-7
pubmed: 23878182
Int J Infect Dis. 2017 Jan;54:121-128
pubmed: 27939768
Open Forum Infect Dis. 2018 Apr 07;5(4):ofy073
pubmed: 29732381
Lancet Infect Dis. 2016 Nov;16(11):1237-1245
pubmed: 27593584
Travel Med Infect Dis. 2016 Sep - Oct;14(5):506-508
pubmed: 27404665
PLoS One. 2017 Oct 3;12(10):e0185689
pubmed: 28973011
Ann Intern Med. 2017 Jan 17;166(2):99-108
pubmed: 27893080
PLoS Med. 2016 Oct 25;13(10):e1002157
pubmed: 27780196
J Travel Med. 2018 Jan 1;25(1):
pubmed: 30508133
Travel Med Infect Dis. 2019 Nov 5;:101512
pubmed: 31704483
Travel Med Infect Dis. 2016 Jul-Aug;14(4):313-30
pubmed: 27425793
Euro Surveill. 2019 Nov;24(45):
pubmed: 31718742
Cell. 2019 Aug 22;178(5):1057-1071.e11
pubmed: 31442400
Lancet. 2016 Feb 20;387(10020):719-21
pubmed: 26876373
Emerg Infect Dis. 2017 Feb;23(2):324-327
pubmed: 27926355
J Travel Med. 2016 Sep 05;23(6):
pubmed: 27601533
J Travel Med. 2019 Dec 23;26(8):
pubmed: 31616923
Nature. 2017 Jun 15;546(7658):406-410
pubmed: 28538727
J Travel Med. 2019 Oct 14;26(7):
pubmed: 31423536
JAMA. 2017 Jan 3;317(1):59-68
pubmed: 27960197
Clin Microbiol Rev. 2016 Jul;29(3):487-524
pubmed: 27029595
Int J Infect Dis. 2019 Jan;78:39-43
pubmed: 30368020
Travel Med Infect Dis. 2020 Jan - Feb;33:101543
pubmed: 31805400