Expression of the type 1 lysophosphatidic acid receptor in osteoblastic cell lineage controls both bone mineralization and osteocyte specification.
Bone
Knockout mice
LPA(1)
Lpar1
Osteoblast
Osteocyte
Journal
Biochimica et biophysica acta. Molecular and cell biology of lipids
ISSN: 1879-2618
Titre abrégé: Biochim Biophys Acta Mol Cell Biol Lipids
Pays: Netherlands
ID NLM: 101731727
Informations de publication
Date de publication:
08 2020
08 2020
Historique:
received:
05
03
2020
revised:
03
04
2020
accepted:
10
04
2020
pubmed:
25
4
2020
medline:
22
12
2020
entrez:
25
4
2020
Statut:
ppublish
Résumé
Lysphosphatidic acid (LPA) is a major natural bioactive lipid mediator whose biological functions affect multiple organs. These include bone as demonstrated by global Lpar1-knockout mice (Lpar1
Identifiants
pubmed: 32330664
pii: S1388-1981(20)30107-4
doi: 10.1016/j.bbalip.2020.158715
pii:
doi:
Substances chimiques
Receptors, Lysophosphatidic Acid
0
lysophosphatidic acid receptor 1, mouse
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
158715Informations de copyright
Copyright © 2020. Published by Elsevier B.V.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.