Impacts of multi-year field exposure of agricultural soil to macrolide antibiotics on the abundance of antibiotic resistance genes and selected mobile genetic elements.
Antibiotic resistance
Environmental resistome
Macrolides
Soil bacteria
Journal
The Science of the total environment
ISSN: 1879-1026
Titre abrégé: Sci Total Environ
Pays: Netherlands
ID NLM: 0330500
Informations de publication
Date de publication:
20 Jul 2020
20 Jul 2020
Historique:
received:
06
03
2020
revised:
03
04
2020
accepted:
05
04
2020
pubmed:
25
4
2020
medline:
11
7
2020
entrez:
25
4
2020
Statut:
ppublish
Résumé
Exposure of environmental bacteria to antibiotics may be increasing the global resistome. Antibiotic residues are entrained into agricultural soil through the application of animal and human wastes, and irrigation with reclaimed water. The impact of a mixture of three macrolide antibiotics on the abundance of selected genes associated with antibiotic resistance and genetic mobility were determined in a long-term field experiment undertaken in London, Canada. Replicated plots received annual applications of a mixture of erythromycin, clarithromycin and azithromycin every spring since 2010. Each antibiotic was added directly to the soil at a concentration of either 0.1 or 10 mg kg soil
Identifiants
pubmed: 32330714
pii: S0048-9697(20)32033-7
doi: 10.1016/j.scitotenv.2020.138520
pii:
doi:
Substances chimiques
Anti-Bacterial Agents
0
Macrolides
0
Soil
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
138520Informations de copyright
Crown Copyright © 2020. Published by Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.