Epithelial-Myoepithelial Carcinoma of the Lacrimal Gland: Case Report of Youngest Patient.


Journal

Ophthalmic plastic and reconstructive surgery
ISSN: 1537-2677
Titre abrégé: Ophthalmic Plast Reconstr Surg
Pays: United States
ID NLM: 8508431

Informations de publication

Date de publication:
Historique:
pubmed: 26 4 2020
medline: 19 3 2021
entrez: 26 4 2020
Statut: ppublish

Résumé

The authors report a case of extremely uncommon malignancy of lacrimal gland epithelial-myoepithelial carcinoma. This carcinoma is more commonly encountered in salivary glands and comprises 1% of all salivary gland tumors. Its occurrence in the orbit is very rare with only 6 cases reported in the literature, most of which arose in a pleomorphic adenoma. Epithelial-myoepithelial carcinoma is primarily a tumor of older adults, with a peak incidence in the sixth and seventh decades of life. The present case is the youngest patient reported to date and had no history of preexisting neoplasm in the lacrimal gland. Histological diagnosis of epithelial-myoepithelial carcinoma is challenging because of the similarity with other lacrimal gland epithelial tumors like malignant adenoid cystic carcinoma and benign pleomorphic adenomas.

Identifiants

pubmed: 32332692
doi: 10.1097/IOP.0000000000001663
pii: 00002341-202011000-00030
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e141-e144

Références

Singh G, Sharma MC, Agarwal S, et al. Epithelial-myoepithelial carcinoma of the lacrimal gland: a rare case. Ann Diagn Pathol. 2012; 16:292–297
Ostrowski ML, Font RL, Halpern J, et al. Clear cell epithelial-myoepithelial carcinoma arising in pleomorphic adenoma of the lacrimal gland. Ophthalmology. 1994; 101:925–930
Chan WM, Liu DT, Lam LY, et al. Primary epithelial-myoepithelial carcinoma of the lacrimal gland. Arch Ophthalmol. 2004; 122:1714–1717
Wiwatwongwana D, Berean KW, Dolman PJ, et al. Unusual carcinomas of the lacrimal gland: epithelial-myoepithelial carcinoma and myoepithelial carcinoma. Arch Ophthalmol. 2009; 127:1054–1056
Allan C, Gonçalves P, de Lima PP, Monteiro MLR. Epithelial-myoepithelial carcinoma of the lacrimal gland 14 years after en bloc resection of a pleomorphic lacrimal gland adenoma. Ophthal mic Plast Reconstr Surg. 2014; 32:e42–e44
Venkatesulu BP, Pathy S, Vallonthaiel AG, Chawla B. Epithelial-myoepithelial carcinoma of the lacrimal gland from an ex pleomorphic adenoma. BMJ Case Rep. 2015; doi:10.1136/bcr-2015-210795
doi: 10.1136/bcr-2015-210795
Weis E, Rootman J, Joly TJ, et al. Epithelial lacrimal gland tumors: pathologic classification and current understanding. Arch Ophthalmol. 2009; 127:1016–1028
Seethala RR, Barnes EL, Hunt JL. Epithelial-myoepithelial carcinoma: a review of the clinicopathologic spectrum and immunophenotypic characteristics in 61 tumors of the salivary glands and upper aerodigestive tract. Am J Surg Pathol. 2007; 31:44–57
Massimo P, Massimo R, Avellini C, et al. Epithelial-myoepithelial carcinoma of the parotid gland: clinicopathological aspect, diagnosis and surgical consideration. Ann Maxillofac Surg. 2014; 4:99–102
Skinner HD, Garden AS, Rosenthal DI, et al. Outcomes of malignant tumors of the lacrimal apparatus: the University of Texas MD Anderson Cancer Center experience. Cancer. 2011; 117:2801–2810

Auteurs

Shahzan Anjum (S)

Departments of Ocular Pathology.

Sujeeth Modaboyina (S)

Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences.

Seema Sen (S)

Departments of Ocular Pathology.

Mehar Chand Sharma (MC)

Pathology, All India Institute of Medical Sciences, New Delhi, India.

Rachna Meel (R)

Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences.

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