Are pharmacological interventions clinically useful to treat emotionalism after stroke? A Cochrane Review update summary with commentary.
Stroke
affective symptoms
antidepressive agents
crying
laughter
randomized controlled trial
review
Journal
NeuroRehabilitation
ISSN: 1878-6448
Titre abrégé: NeuroRehabilitation
Pays: Netherlands
ID NLM: 9113791
Informations de publication
Date de publication:
2020
2020
Historique:
pubmed:
26
4
2020
medline:
10
10
2020
entrez:
26
4
2020
Statut:
ppublish
Résumé
Emotionalism, i.e. uncontrolled episodes of crying (or less commonly laughing) post stroke that are not triggered by situations that would have previously provoked such behavior occur in stroke survivors, may persist in some, and can be socially embarrassing. To evaluate whether pharmacological interventions are beneficial, acceptable, and safe in the treatment of emotionalism post stroke. A Cochrane review by Allida et al. was summarized with comments. From a total of 7 eligible trials with a total of 239 participants included in the review, five with 213 participants could be used for data extraction. Very low to moderate quality evidence pointed to some beneficial effects of antidepressants in the treatment of emotionalism after stroke. The available data suggest that antidepressants may reduce the frequency and severity of crying or laughing episodes in stroke survivors with emotionalism.
Sections du résumé
BACKGROUND
BACKGROUND
Emotionalism, i.e. uncontrolled episodes of crying (or less commonly laughing) post stroke that are not triggered by situations that would have previously provoked such behavior occur in stroke survivors, may persist in some, and can be socially embarrassing.
OBJECTIVE
OBJECTIVE
To evaluate whether pharmacological interventions are beneficial, acceptable, and safe in the treatment of emotionalism post stroke.
METHODS
METHODS
A Cochrane review by Allida et al. was summarized with comments.
RESULTS
RESULTS
From a total of 7 eligible trials with a total of 239 participants included in the review, five with 213 participants could be used for data extraction. Very low to moderate quality evidence pointed to some beneficial effects of antidepressants in the treatment of emotionalism after stroke.
CONCLUSIONS
CONCLUSIONS
The available data suggest that antidepressants may reduce the frequency and severity of crying or laughing episodes in stroke survivors with emotionalism.
Identifiants
pubmed: 32333559
pii: NRE209003
doi: 10.3233/NRE-209003
doi:
Substances chimiques
Antidepressive Agents
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM