Effect of referral pattern and histopathology grade on surgery for nonmalignant colorectal polyps.


Journal

Gastrointestinal endoscopy
ISSN: 1097-6779
Titre abrégé: Gastrointest Endosc
Pays: United States
ID NLM: 0010505

Informations de publication

Date de publication:
09 2020
Historique:
received: 10 03 2020
accepted: 10 04 2020
pubmed: 26 4 2020
medline: 17 3 2021
entrez: 26 4 2020
Statut: ppublish

Résumé

The incidence of surgery for nonmalignant colorectal polyps is rising. The aims of this study were to evaluate referral patterns to surgery for nonmalignant polyps, to compare outcomes between surgery and endoscopic resection (ER), and to identify factors associated with surgery in a university-based, tertiary care center. Patients referred to colorectal surgery (CRS) for nonmalignant colorectal polyps between 2014 and 2019 were selected from the institution's integrated data repository. Clinical characteristics were obtained through chart review. Multivariate analysis was performed to identify factors associated with surgery for nonmalignant polyps. Six hundred sixty-four patients with colorectal lesions were referred to CRS, of which 315 were for nonmalignant polyps. Most referrals (69%) came from gastroenterologists. Of the 315 cases, 136 underwent surgery and 117 were referred for attempt at ER. Complete ER was achieved in 87.2% (n = 102), with polyp recurrence in 27.2% at a median of 14 months (range, 0-72). When compared with surgery, ER was associated with a lower hospitalization rate (22.2% vs 95.6%; P < .0001), shorter hospital stay (mean, .5 ± .9 vs 2.23 ± 1 days; P < .0001), and fewer adverse events (5.9% vs 22.8%; P = .0002). Intramucosal adenocarcinoma on baseline pathology (odds ratio, 5.7; 95% confidence interval, 1.2-28.2) and referrals by academic gastroenterologists (odds ratio, 2.5; 95% confidence interval, 1.11-5.72) were associated with a higher likelihood of surgery on multivariate analysis. Gastroenterologists commonly refer nonmalignant colorectal polyps to surgery, even though ER is effective and associated with lower morbidity. Both referrals from academic gastroenterologists and baseline pathology of intramucosal adenocarcinoma were factors associated with surgery. All colorectal polyps should be evaluated in a multidisciplinary approach to identify lesions suitable for ER before embarking in surgery.

Sections du résumé

BACKGROUND AND AIMS
The incidence of surgery for nonmalignant colorectal polyps is rising. The aims of this study were to evaluate referral patterns to surgery for nonmalignant polyps, to compare outcomes between surgery and endoscopic resection (ER), and to identify factors associated with surgery in a university-based, tertiary care center.
METHODS
Patients referred to colorectal surgery (CRS) for nonmalignant colorectal polyps between 2014 and 2019 were selected from the institution's integrated data repository. Clinical characteristics were obtained through chart review. Multivariate analysis was performed to identify factors associated with surgery for nonmalignant polyps.
RESULTS
Six hundred sixty-four patients with colorectal lesions were referred to CRS, of which 315 were for nonmalignant polyps. Most referrals (69%) came from gastroenterologists. Of the 315 cases, 136 underwent surgery and 117 were referred for attempt at ER. Complete ER was achieved in 87.2% (n = 102), with polyp recurrence in 27.2% at a median of 14 months (range, 0-72). When compared with surgery, ER was associated with a lower hospitalization rate (22.2% vs 95.6%; P < .0001), shorter hospital stay (mean, .5 ± .9 vs 2.23 ± 1 days; P < .0001), and fewer adverse events (5.9% vs 22.8%; P = .0002). Intramucosal adenocarcinoma on baseline pathology (odds ratio, 5.7; 95% confidence interval, 1.2-28.2) and referrals by academic gastroenterologists (odds ratio, 2.5; 95% confidence interval, 1.11-5.72) were associated with a higher likelihood of surgery on multivariate analysis.
CONCLUSIONS
Gastroenterologists commonly refer nonmalignant colorectal polyps to surgery, even though ER is effective and associated with lower morbidity. Both referrals from academic gastroenterologists and baseline pathology of intramucosal adenocarcinoma were factors associated with surgery. All colorectal polyps should be evaluated in a multidisciplinary approach to identify lesions suitable for ER before embarking in surgery.

Identifiants

pubmed: 32334014
pii: S0016-5107(20)34195-X
doi: 10.1016/j.gie.2020.04.041
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

702-711.e2

Commentaires et corrections

Type : CommentIn
Type : CommentIn

Informations de copyright

Copyright © 2020. Published by Elsevier Inc.

Auteurs

Nabeel Moon (N)

Department of Internal Medicine, University of Florida, Gainesville, Florida, USA.

Mahmoud Aryan (M)

College of Medicine, University of Florida, Gainesville, Florida, USA.

Walid Khan (W)

Department of Internal Medicine, University of Florida, Gainesville, Florida, USA.

Peter Jiang (P)

College of Medicine, University of Florida, Gainesville, Florida, USA.

Ishaan Madhok (I)

Department of Internal Medicine, University of Florida, Gainesville, Florida, USA.

Jake Wilson (J)

Department of Internal Medicine, University of Florida, Gainesville, Florida, USA.

Nicole Ruiz (N)

Department of Internal Medicine, University of Florida, Gainesville, Florida, USA.

Sandeep A Ponniah (SA)

Department of Internal Medicine, University of Florida, Gainesville, Florida, USA.

Donevan R Westerveld (DR)

Department of Internal Medicine, University of Florida, Gainesville, Florida, USA.

Anand Gupte (A)

Division of Gastroenterology and Hepatology, University of Florida, Gainesville, Florida, USA.

Nakechand Pooran (N)

Division of Gastroenterology and Hepatology, University of Florida, Gainesville, Florida, USA.

Bashar Qumseya (B)

Division of Gastroenterology and Hepatology, University of Florida, Gainesville, Florida, USA.

Chris E Forsmark (CE)

Division of Gastroenterology and Hepatology, University of Florida, Gainesville, Florida, USA.

Peter V Draganov (PV)

Division of Gastroenterology and Hepatology, University of Florida, Gainesville, Florida, USA.

Dennis Yang (D)

Division of Gastroenterology and Hepatology, University of Florida, Gainesville, Florida, USA.

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