Antifungal susceptibility testing practices in mycology laboratories in France, 2018.
Antifungal Agents
/ therapeutic use
Disk Diffusion Antimicrobial Tests
/ methods
Drug Resistance, Fungal
France
History, 21st Century
Humans
Laboratories
/ standards
Laboratory Proficiency Testing
/ methods
Microbial Sensitivity Tests
/ methods
Mycology
/ history
Professional Practice
/ standards
Quality Control
Surveys and Questionnaires
Antifungal susceptibility testing
Etest
Laboratory practice
MIC value interpretation
Journal
Journal de mycologie medicale
ISSN: 1773-0449
Titre abrégé: J Mycol Med
Pays: France
ID NLM: 9425651
Informations de publication
Date de publication:
Jun 2020
Jun 2020
Historique:
received:
23
01
2020
revised:
26
03
2020
accepted:
01
04
2020
pubmed:
27
4
2020
medline:
21
10
2020
entrez:
27
4
2020
Statut:
ppublish
Résumé
A survey of mycology laboratories for antifungal susceptibility testing (AFST) was undertaken in France in 2018, to better understand the difference in practices between the participating centers and to identify the difficulties they may encounter as well as eventual gaps with published standards and guidelines. The survey captured information from 45 mycology laboratories in France on how they perform AFST (number of strains tested, preferred method, technical and quality aspects, interpretation of the MIC values, reading and interpretation difficulties). Results indicated that 86% of respondents used Etest as AFST method, with a combination of one to seven antifungal agents tested. Most of the participating laboratories used similar technical parameters to perform their AFST method and a large majority used, as recommended, internal and external quality assessments. Almost all the participating mycology laboratories (98%) reported difficulties to interpret the MIC values, especially when no clinical breakpoints are available. The survey highlighted that the current AFST practices in France need homogenization, particularly for MIC reading and interpretation.
Identifiants
pubmed: 32334948
pii: S1156-5233(20)30068-8
doi: 10.1016/j.mycmed.2020.100970
pii:
doi:
Substances chimiques
Antifungal Agents
0
Types de publication
Historical Article
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
100970Informations de copyright
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