Age related retinal Ganglion cell susceptibility in context of autophagy deficiency.
Cell death in the nervous system
Mitophagy
Journal
Cell death discovery
ISSN: 2058-7716
Titre abrégé: Cell Death Discov
Pays: United States
ID NLM: 101665035
Informations de publication
Date de publication:
2020
2020
Historique:
received:
07
02
2020
accepted:
25
03
2020
entrez:
28
4
2020
pubmed:
28
4
2020
medline:
28
4
2020
Statut:
epublish
Résumé
Glaucoma is a common age-related disease leading to progressive retinal ganglion cell (RGC) death, visual field defects and vision loss and is the second leading cause of blindness in the elderly worldwide. Mitochondrial dysfunction and impaired autophagy have been linked to glaucoma and induction of autophagy shows neuroprotective effects in glaucoma animal models. We have shown that autophagy decreases with aging in the retina and that autophagy can be neuroprotective for RGCs, but it is currently unknown how aging and autophagy deficiency impact RGCs susceptibility and survival. Using the optic nerve crush model in young and olWelcome@1234d
Identifiants
pubmed: 32337073
doi: 10.1038/s41420-020-0257-4
pii: 257
pmc: PMC7165178
doi:
Types de publication
Journal Article
Langues
eng
Pagination
21Informations de copyright
© The Author(s) 2020.
Déclaration de conflit d'intérêts
Conflict of interestThe authors declare that they have no conflict of interest.
Références
Cell Death Dis. 2018 Jul 9;9(7):753
pubmed: 29988039
Int J Mol Sci. 2019 Aug 29;20(17):
pubmed: 31470587
Autophagy. 2018;14(5):915-917
pubmed: 28614042
Aging Cell. 2017 Oct;16(5):912-915
pubmed: 28782921
Autophagy. 2017 Oct 3;13(10):1754-1766
pubmed: 28820284
Nature. 2007 Jun 28;447(7148):1121-5
pubmed: 17589504
Front Cell Neurosci. 2018 Apr 18;12:92
pubmed: 29755319
Aging (Albany NY). 2017 Oct 29;9(10):2163-2189
pubmed: 29081403
J Neurochem. 2015 Apr;133(2):233-41
pubmed: 25683606
Front Behav Neurosci. 2014 May 16;8:181
pubmed: 24904333
Mol Cell Proteomics. 2007 May;6(5):895-907
pubmed: 17264069
J Clin Med. 2019 Aug 15;8(8):
pubmed: 31443184
Prog Mol Biol Transl Sci. 2015;134:315-42
pubmed: 26310163
Eye (Lond). 2020 Jan;34(1):29-39
pubmed: 31645673
Prog Retin Eye Res. 2015 Jan;44:62-85
pubmed: 25461968
Cell Biol Int. 2017 Sep;41(9):1039-1047
pubmed: 28685977
Cell Transplant. 2019 May;28(5):585-595
pubmed: 30961359
Int J Mol Sci. 2018 Dec 03;19(12):
pubmed: 30513899
PLoS One. 2017 Apr 6;12(4):e0175451
pubmed: 28384305
Cell Death Differ. 2015 Mar;22(3):476-87
pubmed: 25501597
Nature. 2004 Dec 23;432(7020):1032-6
pubmed: 15525940
Front Pharmacol. 2014 Dec 04;5:267
pubmed: 25538619
Int J Mol Med. 2011 Oct;28(4):505-11
pubmed: 21617844
Biochem Biophys Res Commun. 2014 Feb 7;444(2):182-8
pubmed: 24440703
Curr Neuropharmacol. 2018;16(7):903-918
pubmed: 28677495
Front Physiol. 2017 Aug 24;8:595
pubmed: 28883796
Redox Rep. 2003;8(2):69-79
pubmed: 12804009
Cell Death Dis. 2014 Nov 27;5:e1545
pubmed: 25429622
Cell Transplant. 2015;24(9):1829-44
pubmed: 25299378
Mol Vis. 2016 Dec 30;22:1503-1513
pubmed: 28050123
Nat Commun. 2018 Sep 14;9(1):3755
pubmed: 30217973
Autophagy. 2014 Mar;10(3):480-96
pubmed: 24468901
Int Ophthalmol. 2019 Oct;39(10):2303-2312
pubmed: 30637543
Longev Healthspan. 2014 May 01;3:6
pubmed: 24860647
Proc Natl Acad Sci U S A. 1992 Nov 1;89(21):10449-53
pubmed: 1438232
Sci Rep. 2016 Jul 18;6:29759
pubmed: 27425789
Cell Death Differ. 2013 Jan;20(1):31-42
pubmed: 22743996
J Mol Neurosci. 2008 Jul;35(3):253-8
pubmed: 18551258
Exp Eye Res. 2016 Mar;144:46-53
pubmed: 26321509
Front Mol Neurosci. 2018 Sep 28;11:350
pubmed: 30323741
Hum Mol Genet. 2017 Nov 15;26(22):4451-4464
pubmed: 29036575
J Neurosci. 2011 Jul 13;31(28):10249-61
pubmed: 21753002
Biochim Biophys Acta. 2016 Jan;1860(1 Pt B):246-51
pubmed: 26141743
Nature. 2006 Jun 15;441(7095):880-4
pubmed: 16625205
Cells. 2018 May 05;7(5):
pubmed: 29734735
Cell Death Dis. 2014 Sep 04;5:e1403
pubmed: 25188513
Indian J Ophthalmol. 2014 May;62(5):529-37
pubmed: 24881596
Rev Neurosci. 2019 Mar 06;30(7):729-742
pubmed: 30840597
Nature. 2006 Jun 15;441(7095):885-9
pubmed: 16625204
Antioxid Redox Signal. 2018 Dec 10;29(17):1727-1745
pubmed: 28899199
Mol Vis. 2008 Aug 22;14:1540-8
pubmed: 18728752
PLoS One. 2015 Oct 23;10(10):e0140919
pubmed: 26496696
Front Immunol. 2018 Jun 06;9:1287
pubmed: 29951055
Front Neurosci. 2018 Dec 03;12:865
pubmed: 30559639
Int J Mol Sci. 2019 Jul 12;20(14):
pubmed: 31336872
Ann N Y Acad Sci. 2007 Feb;1097:64-6
pubmed: 17413012
Antioxid Redox Signal. 2011 Oct 1;15(7):1957-97
pubmed: 21087145
Int J Biochem Cell Biol. 2016 Oct;79:118-127
pubmed: 27586257
J Alzheimers Dis. 2016 Jul 27;54(1):113-21
pubmed: 27472881
Ophthalmology. 2014 Nov;121(11):2081-90
pubmed: 24974815
Hum Genet. 2002 Jan;110(1):52-6
pubmed: 11810296
Cell Death Differ. 2012 Jan;19(1):162-9
pubmed: 21701497
Exp Eye Res. 2019 Sep;186:107702
pubmed: 31238079
Hum Genet. 2002 May;110(5):513-4
pubmed: 12073024
Biochim Biophys Acta. 2012 Dec;1823(12):2297-310
pubmed: 22917578
Autophagy. 2012 Feb 1;8(2):187-99
pubmed: 22240590
Mol Cell Neurosci. 2002 Oct;21(2):301-11
pubmed: 12401449
J Clin Invest. 2015 Apr;125(4):1433-45
pubmed: 25798616
Dev Cell. 2016 Oct 10;39(1):116-130
pubmed: 27693508
J Neurochem. 2013 Dec;127(5):669-80
pubmed: 23721546
Cell Death Differ. 2008 Aug;15(8):1279-90
pubmed: 18369370
Transl Psychiatry. 2017 Oct 10;7(10):e1247
pubmed: 28994820
Neural Regen Res. 2014 Mar 15;9(6):565-74
pubmed: 25206855
Cell Death Dis. 2018 Sep 24;9(10):981
pubmed: 30250019
Exp Eye Res. 2019 Nov;188:107795
pubmed: 31525344
Nat Cell Biol. 2013 Jul;15(7):713-20
pubmed: 23817233
Proc Natl Acad Sci U S A. 2010 Aug 10;107(32):14164-9
pubmed: 20660724
Nat Methods. 2016 Sep;13(9):731-40
pubmed: 27348712
Invest Ophthalmol Vis Sci. 2015 Sep;56(10):6095-112
pubmed: 26393669
Aging Cell. 2013 Jun;12(3):478-88
pubmed: 23521856
Mol Cell. 2019 Oct 17;76(2):268-285
pubmed: 31585693
Cell Death Differ. 2015 Mar;22(3):419-32
pubmed: 25215947
Autophagy. 2014 Apr;10(4):549-51
pubmed: 24657946
Nature. 2015 Aug 20;524(7565):309-314
pubmed: 26266977
Subcell Biochem. 2018;90:25-47
pubmed: 30779005
Sci Rep. 2017 Oct 4;7(1):12685
pubmed: 28978942
Mol Neurobiol. 2013 Dec;48(3):819-28
pubmed: 23709342