Epidemiology of multimorbidity in conditions of extreme poverty: a population-based study of older adults in rural Burkina Faso.


Journal

BMJ global health
ISSN: 2059-7908
Titre abrégé: BMJ Glob Health
Pays: England
ID NLM: 101685275

Informations de publication

Date de publication:
2020
Historique:
received: 18 10 2019
revised: 11 02 2020
accepted: 15 02 2020
entrez: 28 4 2020
pubmed: 28 4 2020
medline: 25 6 2021
Statut: epublish

Résumé

Multimorbidity is a health issue of increasing importance worldwide, and is likely to become particularly problematic in low-income countries (LICs) as they undergo economic, demographic and epidemiological transitions. Knowledge of the burden and consequences of multimorbidity in LICs is needed to inform appropriate interventions. A cross-sectional household survey collected data on morbidities and frailty, disability, quality of life and physical performance on individuals aged over 40 years of age living in the Nouna Health and Demographic Surveillance System area in northwestern Burkina Faso. We defined multimorbidity as the occurrence of two or more conditions, and evaluated the prevalence of and whether this was concordant (conditions in the same morbidity domain of communicable, non-communicable diseases (NCDs) or mental health (MH)) or discordant (conditions in different morbidity domains) multimorbidity. Finally, we fitted multivariable regression models to determine associated factors and consequences of multimorbidity. Multimorbidity was present in 22.8 (95% CI, 21.4 to 24.2) of the study population; it was more common in females, those who are older, single, more educated, and wealthier. We found a similar prevalence of discordant 11.1 (95% CI, 10.1 to 12.2) and concordant multimorbidity 11.7 (95% CI, 10.6 to 12.8). After controlling for age, sex, marital status, education, and wealth, an increasing number of conditions was strongly associated with frailty, disability, low quality of life, and poor physical performance. We found no difference in the association between concordant and discordant multimorbidity and outcomes, however people who were multimorbid with NCDs alone had better outcomes than those with multimorbidity with NCDs and MH disorders or MH multimorbidity alone. Multimorbidity is prevalent in this poor, rural population and is associated with markers of decreased physical performance and quality of life. Preventative and management interventions are needed to ensure that health systems can deal with increasing multimorbidity and its downstream consequences.

Identifiants

pubmed: 32337079
doi: 10.1136/bmjgh-2019-002096
pii: bmjgh-2019-002096
pmc: PMC7170422
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e002096

Subventions

Organisme : NHLBI NIH HHS
ID : R01 HL141053
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG059504
Pays : United States
Organisme : Wellcome Trust
ID : 210479/Z/18/Z
Pays : United Kingdom
Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : NIAID NIH HHS
ID : T32 AI007433
Pays : United States
Organisme : NIAID NIH HHS
ID : P30 AI060354
Pays : United States
Organisme : NCATS NIH HHS
ID : KL2 TR003143
Pays : United States

Commentaires et corrections

Type : ErratumIn

Informations de copyright

© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

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Auteurs

Maria Lisa Odland (ML)

Institute of Applied Health Research, University of Birmingham, Birmingham, UK.

Collin Payne (C)

School of Demography, The Australian National University, Canberra, Australian Capital Territory, Australia.

Miles D Witham (MD)

AGE Research Group, NIHR Newcastle Biomedical Research Centre, Newcastle University, Newcastle upon Tyne, UK.
Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.

Mark J Siedner (MJ)

Massachusetts General Hospital, Boston, Massachusetts, USA.
Africa Health Research Institute, KwaZulu-Natal, South Africa.

Till Bärnighausen (T)

Africa Health Research Institute, KwaZulu-Natal, South Africa.
Heidelberg Institute of Global Health (HIGH), Faculty of Medicine and University Hospitals, University of Heidelberg, Heidelberg, Germany.

Mamadou Bountogo (M)

Centre de Recherche en Sante de Nouna, Nouna, Burkina Faso.

Boubacar Coulibaly (B)

Centre de Recherche en Sante de Nouna, Nouna, Burkina Faso.

Pascal Geldsetzer (P)

Division of Primary Care and Population Health, Department of Medicine, Stanford University, Stanford, California, USA.

Guy Harling (G)

Africa Health Research Institute, KwaZulu-Natal, South Africa.
Institute for Global Health, University College London, London, UK.
MRC/Wits Rural Public Health & Health Transitions Research Unit (Agincourt), University of the Witwatersrand, Johannesburg-Braamfontein, South Africa.
Department of Epidemiology & Harvard Center for Population and Development Studies, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

Jennifer Manne-Goehler (J)

Division of Infectious Diseases, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Lucienne Ouermi (L)

Centre de Recherche en Sante de Nouna, Nouna, Burkina Faso.

Ali Sie (A)

Centre de Recherche en Sante de Nouna, Nouna, Burkina Faso.

Justine I Davies (JI)

Institute of Applied Health Research, University of Birmingham, Birmingham, UK.
MRC/Wits Rural Public Health & Health Transitions Research Unit (Agincourt), University of the Witwatersrand, Johannesburg-Braamfontein, South Africa.

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