Extramedullary Plasmacytoma Involving the Heart: A Case Report and Focused Literature Review.
chemotherapy
computed tomography angiography
echocardiography
heart
magnetic resonance imaging
plasmacytoma
positron emission tomography-computed tomography
radiotherapy
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
25 Mar 2020
25 Mar 2020
Historique:
entrez:
28
4
2020
pubmed:
28
4
2020
medline:
28
4
2020
Statut:
epublish
Résumé
Cardiac tumors are extremely rare. Here, we report an unusual case of cardiac plasmacytoma that occurred 11 years after complete remission of the original multiple myeloma (MM). The tumor primarily manifested as a solitary extramedullary plasmacytoma (SEP) with extensive infiltration into the heart and large vessels. There was no evidence of systemic involvement. The relapsing tumor assumed a unique immunophenotype from CD138+/CD38+/CD56- to CD138-/CD38+/CD56-. The patient responded to chemotherapy consisting of carfilzomib, cyclophosphamide, and dexamethasone. This case highlights the importance of multimodal imaging evaluation and tissue diagnosis for accurately characterizing this rare disorder.
Identifiants
pubmed: 32337142
doi: 10.7759/cureus.7418
pmc: PMC7182159
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e7418Informations de copyright
Copyright © 2020, Guan et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
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