Insulinoma as a Potential Insidious Presenter in Medical Refractory Epilepsy.
Journal
Neuro endocrinology letters
ISSN: 2354-4716
Titre abrégé: Neuro Endocrinol Lett
Pays: Sweden
ID NLM: 8008373
Informations de publication
Date de publication:
Apr 2020
Apr 2020
Historique:
received:
04
08
2019
accepted:
12
12
2019
pubmed:
28
4
2020
medline:
26
8
2021
entrez:
28
4
2020
Statut:
ppublish
Résumé
Insulinoma as a cause of epileptic seizure has been thoroughly described but often not considered in differentials for previously established diagnoses of seizure disorder. Hypoglycemic symptoms can mimic neurological disorders such as epilepsy. A 52-year-old woman presented with a history of epilepsy on anti-epileptic drugs (AEDs) developed repeated episodes consisting of seizures and neuropsychiatric symptoms with no predisposing factors for epilepsy at age 52. She had received full AED treatment before the possibility of hypoglycemia was considered. Following a clinical diagnosis of insulinoma, distal pancreatectomy was performed, and her seizures did not occur again. The early diagnosis of insulinoma requires vigilance, not only for hypoglycemia in patients with neuropsychiatric symptoms, but also for the possible masking effects of a history of epilepsy and preceding AED usage.
Sections du résumé
BACKGROUND
BACKGROUND
Insulinoma as a cause of epileptic seizure has been thoroughly described but often not considered in differentials for previously established diagnoses of seizure disorder. Hypoglycemic symptoms can mimic neurological disorders such as epilepsy.
CASE PRESENTATION
METHODS
A 52-year-old woman presented with a history of epilepsy on anti-epileptic drugs (AEDs) developed repeated episodes consisting of seizures and neuropsychiatric symptoms with no predisposing factors for epilepsy at age 52. She had received full AED treatment before the possibility of hypoglycemia was considered. Following a clinical diagnosis of insulinoma, distal pancreatectomy was performed, and her seizures did not occur again.
CONCLUSION
CONCLUSIONS
The early diagnosis of insulinoma requires vigilance, not only for hypoglycemia in patients with neuropsychiatric symptoms, but also for the possible masking effects of a history of epilepsy and preceding AED usage.
Substances chimiques
Anticonvulsants
0
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM