Inhibitory effect of particulate matter on toll-like receptor 9 stimulated dendritic cells by downregulating mitogen-activated protein kinase and NF-κB pathway.
Animals
Cytokines
/ drug effects
Dendritic Cells
/ drug effects
Female
Gasoline
/ adverse effects
Humans
Mice
Mitogen-Activated Protein Kinases
/ drug effects
Models, Animal
NF-kappa B
/ drug effects
Particulate Matter
/ adverse effects
Signal Transduction
/ drug effects
Toll-Like Receptor 9
/ drug effects
Diesel particulate matter
MAPK
NF-κB
TLR
inhibitory effect
Journal
Journal of toxicology and environmental health. Part A
ISSN: 1528-7394
Titre abrégé: J Toxicol Environ Health A
Pays: England
ID NLM: 100960995
Informations de publication
Date de publication:
02 05 2020
02 05 2020
Historique:
pubmed:
29
4
2020
medline:
26
1
2021
entrez:
29
4
2020
Statut:
ppublish
Résumé
Ambient particulate matter (PM) is associated with adverse health consequences. However, the influence of PM on the innate immune system is poorly understood. The aim of the present study was to examine the effect of diesel particulate matter 2.5 μm (PM
Identifiants
pubmed: 32340567
doi: 10.1080/15287394.2020.1756018
doi:
Substances chimiques
Cytokines
0
Gasoline
0
NF-kappa B
0
Particulate Matter
0
Toll-Like Receptor 9
0
Mitogen-Activated Protein Kinases
EC 2.7.11.24
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM