Heart-brain interactions shape somatosensory perception and evoked potentials.
Adult
Attention
/ physiology
Awareness
/ physiology
Brain
/ physiology
Brain Mapping
/ methods
Consciousness
/ physiology
Electrocardiography
/ methods
Electroencephalography
/ methods
Evoked Potentials
/ physiology
Evoked Potentials, Somatosensory
/ physiology
Female
Heart
/ physiology
Heart Rate
/ physiology
Humans
Interoception
/ physiology
Male
Perception
/ physiology
Somatosensory Cortex
/ physiology
EEG
body–brain interaction
consciousness
rhythms
somatosensory awareness
Journal
Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876
Informations de publication
Date de publication:
12 05 2020
12 05 2020
Historique:
pubmed:
29
4
2020
medline:
22
8
2020
entrez:
29
4
2020
Statut:
ppublish
Résumé
Even though humans are mostly not aware of their heartbeats, several heartbeat-related effects have been reported to influence conscious perception. It is not clear whether these effects are distinct or related phenomena, or whether they are early sensory effects or late decisional processes. Combining electroencephalography and electrocardiography, along with signal detection theory analyses, we identify two distinct heartbeat-related influences on conscious perception differentially related to early vs. late somatosensory processing. First, an effect on early sensory processing was found for the heartbeat-evoked potential (HEP), a marker of cardiac interoception. The amplitude of the prestimulus HEP negatively correlated with localization and detection of somatosensory stimuli, reflecting a more conservative detection bias (criterion). Importantly, higher HEP amplitudes were followed by decreases in early (P50) as well as late (N140, P300) somatosensory-evoked potential (SEP) amplitudes. Second, stimulus timing along the cardiac cycle also affected perception. During systole, stimuli were detected and correctly localized less frequently, relating to a shift in perceptual sensitivity. This perceptual attenuation was accompanied by the suppression of only late SEP components (P300) and was stronger for individuals with a more stable heart rate. Both heart-related effects were independent of alpha oscillations' influence on somatosensory processing. We explain cardiac cycle timing effects in a predictive coding account and suggest that HEP-related effects might reflect spontaneous shifts between interoception and exteroception or modulations of general attentional resources. Thus, our results provide a general conceptual framework to explain how internal signals can be integrated into our conscious perception of the world.
Identifiants
pubmed: 32341167
pii: 1915629117
doi: 10.1073/pnas.1915629117
pmc: PMC7229654
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
10575-10584Commentaires et corrections
Type : ErratumIn
Informations de copyright
Copyright © 2020 the Author(s). Published by PNAS.
Déclaration de conflit d'intérêts
The authors declare no competing interest.
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